Allantoin for Eczema (Atopic Dermatitis)

A gentle smoother and skin-soother. Reduces flakiness and helps the surface look more even.

Why it works for Eczema (Atopic Dermatitis)

Soothes irritated skin and softens rough, scaly patches. Allantoin helps new skin grow and gently smooths the thick, scaly areas that come with long-term eczema. The FDA recognizes it as a skin protectant, and it shows up in many National Eczema Association-approved moisturizers. It is great for calming inflamed skin between flares.

How Allantoin works

Keratolytic and soothing agent that promotes cell proliferation and smooths rough texture.

Evidence

4 citations from our ingredient database. Full citation list on the Allantoin ingredient page.

journal2025

Xu Z et al., Efficacy and Safety of Topical Compound Heparin Sodium Allantoin Gel for the Treatment of Rosacea, Journal of Cosmetic Dermatology 2025;24(4):e70129 — RCT (n=82, 12 weeks): allantoin gel improved erythema and alleviated itching/burning vs traditional therapy

journal2024

Tan C et al., The combination of allantoin, bisabolol, D-panthenol and dipotassium glycyrrhizinate mitigates UVB-induced PGE2 synthesis by keratinocytes, International Journal of Cosmetic Science 2024;46(5):691-701 — in vitro: allantoin combination reduced UVB-induced PGE2, IL-1α, IL-6, IL-8, TNFα

journal2023

Saucedo-Acuna RA et al. (Mexico), Characterization and In Vivo Assay of Allantoin-Enriched Pectin Hydrogel for the Treatment of Skin Wounds, International Journal of Molecular Sciences 2023;24(8):7377 — allantoin-pectin hydrogel reduced wound healing time by ~71% with complete closure at day 15 in rat model

journal2022

Leeyaphan C et al., A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, B. parkii extract, A. spinosa kernel oil, A. barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo, Journal of Cosmetic Dermatology 2022;21(2):679-688 — allantoin-containing adsorbent lotion equivalent to low-potency steroid for intertrigo

Products with Allantoin in our catalog

These are the catalog products that list Allantoin as a tracked ingredient.

First Aid Beauty

Pure Skin Face Cleanser

$26 · Cleanser

The Inkey List

Oat Cleansing Balm

$11 · Cleanser

Pixi

Glow Tonic 5% Glycolic Acid Exfoliating Toner

$18 · Toner

Torriden

Dive-In Low Molecular Hyaluronic Acid Toner

$19 · Toner

Peach Slices

Acne Exfoliating Toner

$13 · Toner

Torriden

Dive-In Low Molecular Hyaluronic Acid Serum

$20 · Serum

Full Allantoin guide →Eczema (Atopic Dermatitis) overview →