Pick any two ingredients from our database. We'll tell you if they pair well, conflict, or have no known interaction, backed by the same research that powers the ingredient pages.
Every conflict in this database comes from the same peer-reviewed literature that backs our ingredient evidence tiers, not from Reddit threads or marketing copy. A conflict is flagged when published research documents barrier disruption, ingredient degradation, or pH incompatibility between two actives.
Severity reflects the published risk level: high means documented irritation or efficacy loss in controlled studies; medium means cautious separation is recommended by dermatologists but not always studied directly; low means the interaction is real but manageable with normal pacing.
A “no known interaction” result doesn't mean safe for everyone. Skin is individual. Use it as a starting point, not a guarantee. Read the full evidence behind each ingredient on its ingredient page.