Beta-Glucan for Eczema (Atopic Dermatitis)

A heavy-duty hydrator that also reduces irritation. Often called "better than hyaluronic acid" for sensitive skin.

Why it works for Eczema (Atopic Dermatitis)

Calms the inflammation behind eczema and strengthens the skin barrier. Beta-glucan comes from oats. It dials down the immune signals that drive eczema itch and flares. Lab work and small studies show it soothes and supports the barrier. Colloidal oatmeal, which is rich in beta-glucan, is an FDA-recognized skin protectant for eczema itch relief.

How Beta-Glucan works

Polysaccharide film-former that hydrates while modulating cutaneous immune response.

Evidence

4 citations from our ingredient database. Full citation list on the Beta-Glucan ingredient page.

review2025

Feng X et al., Exploring the Properties and Application Potential of beta-Glucan in Skin Care, Food Science and Nutrition 2025;13(4):e70212 — review concludes beta-glucan exhibits antioxidant, anti-inflammatory, barrier repair, and moisturizing bioactivities

journal2024

Kussie HC et al., Avenanthramide and beta-Glucan Therapeutics Accelerate Wound Healing Via Distinct and Nonoverlapping Mechanisms, Advances in Wound Care 2024;13(4):155-166 — in vivo: beta-glucan accelerated wound closure with increased angiogenesis

journal2021

Du B et al., Oat β-glucan ameliorates epidermal barrier disruption by upregulating CaSR via dectin-1-mediated ERK/p38 signaling, International Journal of Biological Macromolecules 2021 — mechanism for barrier-repair effects; in-vitro and animal-model evidence

journal2021

Cao Y et al., Administration of skin care regimens containing beta-glucan for skin recovery after fractional laser therapy: A split-face, double-blinded, vehicle-controlled study, Journal of Cosmetic Dermatology 2021;20(6):1756-1762 — Shanghai Tongji U; beta-glucan regimen accelerated recovery of skin inflammation and barrier function after fractional laser

Products with Beta-Glucan in our catalog

These are the catalog products that list Beta-Glucan as a tracked ingredient.

Klairs

Supple Preparation Facial Toner

$22 · Toner

Isntree

Hyaluronic Acid Toner

$18 · Toner

Origins

Mega-Mushroom Relief & Resilience Advanced Face Serum

$72 · Serum

Haruharu Wonder

Black Rice Hyaluronic Anti-Aging Serum

$24 · Serum

iUNIK

Beta-Glucan Power Moisture Serum

$15 · Serum

iUNIK

Beta-Glucan Daily Moisture Cream 60ml

$12 · Moisturizer

Full Beta-Glucan guide →Eczema (Atopic Dermatitis) overview →