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Strong evidence

Niacinamide for Eczema (Atopic Dermatitis)

A multitasker that calms redness, evens out skin tone, and helps oily skin balance out. One of the safest do-a-little-of-everything ingredients.

Why it works for Eczema (Atopic Dermatitis)

Strengthens your skin barrier so it holds water better and reacts less. Niacinamide is vitamin B3. At 2-5% it gets your skin to make more of its own ceramides and barrier proteins, and it calms the inflammation signals behind eczema. A trial (Draelos 2005, PMID:16209160) showed it improved the barrier and made skin less sensitive. It is gentle enough even for an eczema-damaged barrier, and it works well alongside ceramide moisturizers.

How Niacinamide works

Reduces transepidermal water loss, inhibits melanosome transfer, and dampens inflammatory cytokines.