Conditions Melasma Azelaic Acid
Az
Strong evidence

Azelaic Acid for Melasma

Calms redness, fades acne marks, and clears bumps, all without aggravating sensitive skin. Pregnancy-safe.

Why it works for Melasma

Fades dark patches by slowing pigment production, and it also calms inflammation. In a 155-person trial, 20% azelaic acid beat 2% hydroquinone (73% had a good-to-excellent response versus 19%), and later head-to-head trials matched it against 4% hydroquinone. It is safe to use in pregnancy, so it is the first topical to reach for when melasma shows up during pregnancy.

How Azelaic Acid works

Dicarboxylic acid that inhibits tyrosinase and is antimicrobial against C. acnes.