Conditions Melasma Niacinamide
Ni
Strong evidence

Niacinamide for Melasma

A multitasker that calms redness, evens out skin tone, and helps oily skin balance out. One of the safest do-a-little-of-everything ingredients.

Why it works for Melasma

Stops pigment from being passed into your skin's surface cells, so patches look lighter. In a split-face trial of 27 people, 4% niacinamide gave a good-to-excellent improvement in 44% of cases versus 55% for 4% hydroquinone. It works slightly less well but causes far less irritation. It is a good long-term option once you finish a hydroquinone course.

How Niacinamide works

Reduces transepidermal water loss, inhibits melanosome transfer, and dampens inflammatory cytokines.