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Ingredients Brightening Ascorbyl Glucoside
7Ag
Sourced from lab + citrus
Tier · Moderate evidence
Brightening · Antioxidant

Ascorbyl Glucoside

INCI: Ascorbyl Glucoside · Also called: AA2G

A gentler, more stable form of vitamin C. Same brightening benefits with less chance of stinging.

For your skin

A gentler, more stable form of vitamin C. Same brightening benefits with less chance of stinging.

Want the science? Keep reading ↓

Mechanism of action

Glucose-stabilized vitamin C precursor; converts to L-ascorbic acid in skin via alpha-glucosidase.

Why we tier this moderate

6 cited papers across 4 countries. The mechanism is well-described and there's at least one controlled trial in the literature, but we tier this Moderate rather than Strong to stay honest about how many specific papers we cite directly.

3
International
1
Japan
1
European Union
1
France

Read the research

Cited research

🇯🇵

Takada A et al., Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos, International Journal of Molecular Sciences 2024 — significantly reduced solar lentigo hyperpigmentation without adverse effects

2024Positive (efficacy)PMID:39769217View source ↗
🇪🇺

Muller B et al., A Bayesian network meta-analysis of 14 molecules inhibiting UV daylight-induced pigmentation, Journal of the European Academy of Dermatology and Venereology 2024;38(8):1566-1574 — network MA including ascorbyl glucoside 2% among depigmenting agents

2024Meta-analysis (positive)PMID:38433524View source ↗
🌐

Jacques C et al., Ascorbic acid 2-glucoside: An ascorbic acid pro-drug with longer-term antioxidant efficacy in skin, International Journal of Cosmetic Science 2021 — comparable antioxidant protection to higher-dose ascorbic acid with better stability

🇫🇷

Roure R et al., A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing 4-Hexyl-1,3-Phenylenediol and Ascorbic Acid-2-Glucoside in Adult Females, Journal of Drugs in Dermatology 2016;15(6):750-758 — topical ascorbyl glucoside (ascorbic acid-2-glucoside) antiaging RCT

2016Positive (efficacy)PMID:27272084View source ↗
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Stamford NPJ, Stability, transdermal penetration, and cutaneous effects of ascorbic acid and its derivatives, Journal of Cosmetic Dermatology 2012;11(4):310-7

2012Positive (efficacy)PMID:23174055View source ↗
🌐

Hsiao YP et al., Fractional carbon dioxide laser treatment to enhance skin permeation of ascorbic acid 2-glucoside with minimal skin disruption, Dermatologic Surgery 2012 — fractional CO2 laser pretreatment enhances cutaneous delivery of ascorbyl glucoside

Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.