For your skin
A probiotic-based ingredient that strengthens your skin's defenses against irritation and environmental stress.
Want the science? Keep reading ↓Mechanism of action
Probiotic-derived lysate that supports DNA repair response and reinforces skin barrier function.
Why we tier this moderate
6 cited papers across 3 countries. The mechanism is well-described and there's at least one controlled trial in the literature, but we tier this Moderate rather than Strong to stay honest about how many specific papers we cite directly.
Cited research
Zhu X et al., Protective effect of Bifidobacterium animalis CGMCC25262 on HaCaT keratinocytes, International Microbiology 2024;27(5):1417-1428 — B. animalis lysate upregulated HAS-2, AQP3, FLG and reduced RANTES under TNF-α/IFN-γ
Wang Y et al., Short-term skin reactions and changes in stratum corneum following different ways of facial sheet mask usage, Journal of Tissue Viability 2024;33(4):831-839 — evaluated topical bifida ferment lysate masks on skin barrier measures
Wang R et al., The pivotal role of Bifida Ferment Lysate on reinforcing the skin barrier function and maintaining homeostasis of skin defenses in vitro, Journal of Cosmetic Dermatology 2023;22(12):3427-3435 — BFL upregulated barrier and antioxidant genes; reduced inflammatory signaling
Ma X et al., Bifidobacterium infantis strain YLGB-1496 possesses excellent antioxidant and skin barrier-enhancing efficacy in vitro, Experimental Dermatology 2022;31(7):1089-1094 — cell-free culture supernatant showed antioxidant + upregulated skin barrier genes
Fabbrocini G et al., A Randomized, Double-Blind, Placebo-Controlled, Multicentric Study to Evaluate the Efficacy and Tolerability of a Class II Medical Device (containing bifida ferment lysate) in the Treatment of Mild and Moderate Acne, Dermatology and Therapy (Heidelberg) 2022;12(8):1835-1845 — topical bifida-ferment-lysate device reduced acne lesions vs placebo
Guéniche A et al., Bifidobacterium longum lysate, a new ingredient for reactive skin, Experimental Dermatology 2010;19(8):e1-e8 — significant decrease in skin sensitivity and improved barrier function with 10% bacterial extract cream over 2 months
Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.