Ingredients Anti-inflammatory Chamomile
73Cm
Tier · Moderate evidence
Anti-inflammatory · Antioxidant

Chamomile

INCI: Chamomilla Recutita (Matricaria) Flower Extract · Also called: Matricaria, German Chamomile

The classic "tea-bag-on-puffy-eyes" botanical. Calms angry skin via the same anti-inflammatory pathways psoriasis drugs target, just gentler. Good for reactive or rosacea-prone complexions.

For your skin

The classic "tea-bag-on-puffy-eyes" botanical. Calms angry skin via the same anti-inflammatory pathways psoriasis drugs target, just gentler. Good for reactive or rosacea-prone complexions.

Want the science? Keep reading ↓

Mechanism of action

Flavonoid (apigenin) and terpenoid (α-bisabolol, chamazulene) blend that inhibits PI3K/Akt/mTOR and p38 MAPK signaling in inflamed keratinocytes, dampening cytokine release in psoriasiform skin models.

Why we tier this moderate

5 cited papers across 3 countries. The mechanism is well-described and there's at least one controlled trial in the literature, but we tier this Moderate rather than Strong to stay honest about how many specific papers we cite directly.

2
China
2
European Union
1
International

Cited research

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Essential Oil of Matricaria chamomilla Alleviates Psoriatic-Like Skin Inflammation by Inhibiting PI3K/Akt/mTOR and p38MAPK Signaling Pathway, Clinical Cosmetic and Investigational Dermatology 2024

2024Mechanism onlyPMID:38222858View source ↗
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Phytochemical, Technological, and Pharmacological Study on the Galenic Dry Extracts Prepared from German Chamomile Flowers (Romania), Plants 2024

2024Mechanism onlyPMID:38337883View source ↗
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Comparative analysis of whole plant, flower and root extracts of Chamomilla recutita L. (Germany), Frontiers in Immunology 2024

2024Mechanism onlyPMID:38720895View source ↗
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Xu J et al., Therapeutic effects of chamomile volatile oil nanoemulsion/Bletilla striata polysaccharides gels on atopic dermatitis, International Journal of Biological Macromolecules 2024 — topical chamomile volatile oil nanoemulsion (19.07 nm) reduced skin damage, epidermal thickness, and mast cell infiltration in atopic dermatitis mice; rebalanced Th1/Th2

2024Positive — efficacyPMID:39111460View source ↗
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El-Salamouni NS et al. (Egypt), Evaluation of chamomile oil and nanoemulgels as a promising treatment option for atopic dermatitis induced in rats, Expert Opinion on Drug Delivery 2020 — topical chamomile nanoemulgel halved skin healing time vs chamomile oil alone and lowered inflammatory biomarkers in rat AD model

2020Positive — efficacyPMID:31782320View source ↗

Sources: PubMed · KCI · J-Stage · CNKI · Wanfang · SFD · MFDS · Cochrane · SCCS · CIR. Every entry points to a specific document. See methodology for what each outcome label means.