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Ingredients Sun protection Ensulizole
121Es
Tier · Moderate evidence
Sun protection

Ensulizole

INCI: Phenylbenzimidazole Sulfonic Acid · Also called: PBSA, 2-Phenylbenzimidazole-5-Sulfonic Acid, Eusolex 232

A water-soluble UVB filter used in lighter sunscreen emulsions. It supports the labeled SPF without adding as much oil, but it is not broad-spectrum by itself and must be paired with UVA filters.

For your skin

A water-soluble UVB filter used in lighter sunscreen emulsions. It supports the labeled SPF without adding as much oil, but it is not broad-spectrum by itself and must be paired with UVA filters.

Want the science? Keep reading ↓

Mechanism of action

A water-soluble organic UV filter that absorbs primarily UVB radiation. Because it dissolves in the water phase rather than the oil phase, it can reduce the heavy or greasy feel of a chemical sunscreen, but it still requires separate UVA coverage.

Why we tier this moderate

3 cited papers across 2 countries. The mechanism is well-described and there's at least one controlled trial in the literature, but we tier this Moderate rather than Strong to stay honest about how many specific papers we cite directly.

2
European Union
1
International

Cited research

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Barrientos N et al. Allergic contact dermatitis caused by phenylbenzimidazole sulfonic acid included in a sunscreen. Contact Dermatitis. 2019;81(2):151-152.

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Bens G. Sunscreens. Advances in Experimental Medicine and Biology. 2014;810:429-463 — review of organic and inorganic sunscreen filters, their spectral roles, formulation, and safety considerations.

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Leon Z et al. A reversed-phase ion-interaction chromatographic method for in-vitro estimation of the percutaneous absorption of water-soluble UV filters. Analytical and Bioanalytical Chemistry. 2008;391(3):859-866 — evaluated skin absorption of water-soluble UV filters including phenylbenzimidazole sulfonic acid.

Sources: PubMed · KCI · J-Stage · CNKI · Wanfang · SFD · MFDS · Cochrane · SCCS · CIR. Every entry points to a specific document. See methodology for what each outcome label means.