Ingredients Antioxidant Fermented Soy
44Fs
Sourced from lab
Tier · Moderate evidence
Antioxidant · Anti-aging

Fermented Soy

INCI: Glycine Soja Ferment · Also called: Soy Ferment, Nattokinase

Fermented soy compounds that fight environmental damage from sun and pollution while gradually supporting skin firmness.

For your skin

Fermented soy compounds that fight environmental damage from sun and pollution while gradually supporting skin firmness.

Want the science? Keep reading ↓

Mechanism of action

Fermented soy peptides and isoflavones that scavenge free radicals and support extracellular matrix integrity.

Why we tier this moderate

6 cited papers across 3 countries. The mechanism is well-described and there's at least one controlled trial in the literature, but we tier this Moderate rather than Strong to stay honest about how many specific papers we cite directly.

3
Japan
2
International
1
European Union

Cited research

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Wójciak M et al., Protective, Anti-Inflammatory, and Anti-Aging Effects of Soy Isoflavones on Skin Cells: An Overview of In Vitro and In Vivo Studies, Molecules 2024;29(23):5790 — review concludes anti-inflammatory, protective, antioxidant mechanisms support cosmetic anti-aging applications

2024Mechanism onlyPMID:39683947View source ↗
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Rungseevijitprapa W et al., Improvement of Biophysical Skin Parameters of Topically Applied Fermented Soybean Extract-Loaded Niosomes with No Systemic Toxicity in Ovariectomized Rats, Pharmaceutics 2021;13(7):1068 — topical Aspergillus oryzae-fermented soybean niosomes improved skin hydration and elasticity comparable to estrogen without systemic effects

2021Positive — efficacyPMID:34371759View source ↗
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Nagino T et al., Effects of fermented soymilk with Lactobacillus casei Shirota on skin condition and the gut microbiota: a randomised clinical pilot trial, Beneficial Microbes 2018;9(2):209-218 — daily fermented soymilk improved skin condition and modulated gut microbiota

2018Positive — efficacyPMID:29264969View source ↗
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Kano M et al., Oral Administration of Fermented Soymilk Products Protects the Skin of Hairless Mice against Ultraviolet Damage, Nutrients 2016;8(8):514 — fermentation increased isoflavone bioavailability and reduced UV-induced ROS and photodamage in hairless mouse skin

2016Mechanism onlyPMID:27556484View source ↗
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Miyazaki K et al., Topical application of Bifidobacterium-fermented soy milk extract containing genistein and daidzein improves rheological and physiological properties of skin, Journal of Cosmetic Science 2004;55(5):473-9 — topical fermented soy extract increased hyaluronic acid production and improved skin elasticity and hydration in animal and human studies

2004Positive — efficacyPMID:15608997View source ↗
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Wei H et al., Antioxidant and antipromotional effects of the soybean isoflavone genistein, Proceedings of the Society for Experimental Biology and Medicine 1995;208(1):124-30 — in-vitro antioxidant mechanism

1995Mechanism onlyPMID:7892286View source ↗

Sources: PubMed · KCI · J-Stage · CNKI · Wanfang · SFD · MFDS · Cochrane · SCCS · CIR. Every entry points to a specific document. See methodology for what each outcome label means.