Ingredients Sun protection Octinoxate
99Oc
Tier · Moderate evidence
Sun protection

Octinoxate

INCI: Ethylhexyl Methoxycinnamate · Also called: Ethylhexyl Methoxycinnamate, Octyl Methoxycinnamate, OMC, Parsol MCX

The UVB workhorse behind most chemical sunscreens: effective, well-tolerated, and found in over 90% of chemical-filter formulas in the US. Important caveat: it covers UVB only, so it always needs a UVA partner (typically avobenzone). Also banned in Hawaii and reef-sensitive areas due to coral toxicity, so check the label if environmental impact matters to you.

For your skin

The UVB workhorse behind most chemical sunscreens: effective, well-tolerated, and found in over 90% of chemical-filter formulas in the US. Important caveat: it covers UVB only, so it always needs a UVA partner (typically avobenzone). Also banned in Hawaii and reef-sensitive areas due to coral toxicity, so check the label if environmental impact matters to you.

Want the science? Keep reading ↓

Mechanism of action

Octinoxate (ethylhexyl methoxycinnamate) is a cinnamate ester that absorbs UVB radiation (290–320 nm) with peak absorption at ~311 nm. It does not cover UVA wavelengths (320–400 nm) and must be combined with a UVA filter for broad-spectrum protection. The most frequently used UVB filter in US chemical sunscreen formulations; FDA-approved OTC drug active at up to 7.5%. Banned in Hawaii, Palau, and several other jurisdictions due to evidence of aquatic toxicity to coral reefs.

Why we tier this moderate

1 cited paper across 1 country. The mechanism is well-described and there's at least one controlled trial in the literature, but we tier this Moderate rather than Strong to stay honest about how many specific papers we cite directly.

1
India

Cited research

🇮🇳

Rai R, Shanmuga SC, Srinivas CR. Update on Photoprotection. Indian J Dermatol. 2012;57(5):335-42.

2012Mechanism onlyPMID:23112351View source ↗

Sources: PubMed · KCI · J-Stage · CNKI · Wanfang · SFD · MFDS · Cochrane · SCCS · CIR. Every entry points to a specific document. See methodology for what each outcome label means.