Ingredients Anti-acne Salicylic Acid
8Sa
Sourced from lab
Tier · Strong evidence
Anti-acne · Exfoliating

Salicylic Acid

INCI: Salicylic Acid · Also called: BHA, Beta Hydroxy Acid

Goes into your pores and dissolves the oil and dead skin clogging them. Best for blackheads, whiteheads, and oily, acne-prone skin.

For your skin

Goes into your pores and dissolves the oil and dead skin clogging them. Best for blackheads, whiteheads, and oily, acne-prone skin.

Want the science? Keep reading ↓

Mechanism of action

Oil-soluble exfoliant that penetrates sebum to dissolve intra-follicular keratin plugs.

Why we tier this strong

7 cited papers across 5 countries. Multiple positive efficacy results plus regulatory backing. Clears our published bar (Strong = 15+ studies with multiple randomized controlled trials (RCTs), or a single large longitudinal cohort).

2
China
2
United States
1
International
1
Korea
1
European Union

Layering matrix

!Combine carefully
  • Retinol + salicylic acid can over-exfoliate and damage the barrier. Alternate nights.

  • Tretinoin + salicylic acid — major irritation risk. Strict separation required.

  • AHA + BHA stacking risks over-exfoliation. Use a pre-formulated AHA/BHA product or alternate days.

Read the research

Compare with

Cited research

🇨🇳

Liu Y et al., Clinical Efficacy of a Salicylic Acid-Containing Gel on Acne Management and Skin Barrier Function: A 21-Day Prospective Study, Journal of Cosmetic Dermatology 2025;24(7):e70353 — salicylic acid gel reduced acne lesions, regulated sebum, improved hydration and barrier function

2025Positive — efficacyPMID:40682377View source ↗
🇨🇳

Ye R et al., 2% supramolecular salicylic acid hydrogel vs. adapalene gel in mild to moderate acne vulgaris: multicenter, randomized, evaluator-blind, parallel-controlled trial, Journal of Cosmetic Dermatology 2024;23(6):2125-2134 — 2% SSA hydrogel was equally effective as adapalene gel for mild-to-moderate acne

2024Positive — efficacyPMID:38590107View source ↗
🌐

Liu H et al., Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid for acne, Cochrane Database of Systematic Reviews 2020;5:CD011368 — conclusion: clinical benefit is unclear

2020Meta-analysis — mixedPMID:32356369View source ↗
🇰🇷

MFDS Approved Functional Cosmetic Active — Salicylic Acid (anti-acne). Korean Ministry of Food and Drug Safety, Cosmetic Functional Active Ingredient List — the sole approved anti-acne functional cosmetic active in the Korean Functional Cosmetics Codex

2020Regulatory approvalMFDS:SalicylicAcid-AntiAcneView source ↗
🇺🇸

CIR Amended Safety Assessment of Salicylic Acid and Salicylates as Used in Cosmetics (Johnson et al.), final amended report April 2019

2019Safety assessmentCIR-SalicylicAcidView source ↗
🇪🇺

SCCS Opinion on the safety of cosmetic ingredient salicylic acid (CAS 69-72-7) - Submission I, SCCS/1601/18, final version 21 December 2018

2018Safety assessmentSCCS/1601/18View source ↗
🇺🇸

Arif T, Salicylic acid as a peeling agent: a comprehensive review, Clinical, Cosmetic and Investigational Dermatology 2015;8:455-61

2015Positive — efficacyPMID:26347269View source ↗

Sources: PubMed · KCI · J-Stage · CNKI · Wanfang · SFD · MFDS · Cochrane · SCCS · CIR. Every entry points to a specific document. See methodology for what each outcome label means.