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Ingredients Barrier repair Sea Buckthorn Oil
58Sb
Tier · Moderate evidence
Barrier repair · Anti-inflammatory · Antioxidant

Sea Buckthorn Oil

INCI: Hippophae Rhamnoides Oil · Also called: Hippophae Oil, Sea Buckthorn Seed Oil

A vivid orange plant oil packed with omega-7. Calms reactive, atopic-prone skin and helps refill the lipid barrier without feeling heavy.

For your skin

A vivid orange plant oil packed with omega-7. Calms reactive, atopic-prone skin and helps refill the lipid barrier without feeling heavy.

Want the science? Keep reading ↓

Mechanism of action

Carotenoid- and omega-7-rich plant oil that suppresses NF-κB and STAT1 signaling, reducing Th2 chemokine release in inflamed skin while supplying barrier lipids.

Why we tier this moderate

5 cited papers across 1 country. The mechanism is well-described and there's at least one controlled trial in the literature, but we tier this Moderate rather than Strong to stay honest about how many specific papers we cite directly.

5
International

Cited research

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Song X et al., The Role of Sea Buckthorn in Skin and Mucosal Health: A Review from an Anti-Inflammatory Perspective, Frontiers in Pharmacology 2025

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Dudau M et al., A Fatty Acid Fraction Purified From Sea Buckthorn Seed Oil Has Regenerative Properties on Normal Skin Cells, Frontiers in Pharmacology 2021;12:737571

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Balkrishna A et al., Cytokines Driven Anti-Inflammatory and Anti-Psoriasis Like Efficacies of Nutraceutical Sea Buckthorn (Hippophae rhamnoides) Oil, Frontiers in Pharmacology 2019;10:1186 — sea buckthorn oil inhibited reactive nitrogen species and suppressed inflammatory cytokines in cell and animal psoriasis-like models

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Hou DD et al., Sea Buckthorn (Hippophae rhamnoides L.) Oil Improves Atopic Dermatitis-Like Skin Lesions via Inhibition of NF-kappaB and STAT1 Activation, Skin Pharmacology and Physiology 2017;30(5):268-276

2017Positive (efficacy)PMID:28873377View source ↗
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Khan BA, Akhtar N, Hippophae rhamnoides oil-in-water (O/W) emulsion improves barrier function in healthy human subjects, Pakistan Journal of Pharmaceutical Sciences 2014;27(6 Spec No):1919-22 — 84-day study (n=13) showed 5% sea buckthorn emulsion significantly improved hydration and reduced TEWL vs placebo base

2014Positive (efficacy)PMID:25362595View source ↗

Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.