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Shop Ma:nyo Factory Galactomyces Niacin Whitening Essence
Essence
Ma:nyo Factory

Galactomyces Niacin Whitening Essence

~$30· 1.69 fl oz
Dark spotsRadianceUneven textureVisible pores

What it's good for

Key actives from our research database. Click any to read the full evidence dossier.

  • Galactomyces FermentModerate evidenceFull dossier ↗

    A yeast-based ingredient that brightens skin tone and refines the look of pores. Made famous by SK-II essences.

    Good for: Brightening, Hydrating

  • NiacinamideStrong evidenceFull dossier ↗

    A multitasker that calms redness, evens out skin tone, and helps oily skin balance out. One of the safest do-a-little-of-everything ingredients.

    Good for: Brightening, Barrier repair, Anti-inflammatory

Evidence behind the ingredients

Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.

Galactomyces FermentModerate evidence5 citations

A yeast-based ingredient that brightens skin tone and refines the look of pores. Made famous by SK-II essences.

Snowball JM et al., Integration of Transcriptomics and Spatial Biology Analyses Reveals Galactomyces Ferment Filtrate Promotes Epidermal Interconnectivity, International Journal of Cosmetic Science 2024

2024Mechanism onlyPMID:38924095View source ↗

Miyamoto K et al., Significant Reversal of Facial Wrinkle, Pigmented Spot and Roughness by Daily Application of Galactomyces Ferment Filtrate-Containing Skin Products for 12 Months—An 11-Year Longitudinal Skin Aging Rejuvenation Study, Journal of Clinical Medicine 2023;12(3):1168 — 86 female volunteers; 12-month daily application reversed wrinkle, spot, and roughness markers that had deteriorated over the prior 11-year interval

2023Positive (efficacy)PMID:36769815View source ↗

Yan X et al., Galactomyces Ferment Filtrate Potentiates an Anti-Inflammaging System in Keratinocytes, Journal of Clinical Medicine 2022;11(21):6338 — GFF activates AHR/NRF2 antioxidant signaling, attenuating inflammaging

2022Mechanism onlyPMID:36362566View source ↗
NiacinamideStrong evidence10 citations

A multitasker that calms redness, evens out skin tone, and helps oily skin balance out. One of the safest do-a-little-of-everything ingredients.

Moro F et al., Skin Cancer Prevention and Antiaging: Role of Nicotinamide, International Journal of Molecular Sciences 2026

2026Mechanism onlyPMID:42278444View source ↗

Passeron T et al., An Investigator-Blinded, Randomized Trial of a Broad-Spectrum Sunscreen Containing Sclareolide and Niacinamide, Dermatology and Therapy (Heidelberg) 2026

2026Positive (efficacy)PMID:41240206View source ↗

Vergilio MM et al., Topical Formulation with Niacinamide Combined with 5 MHz Ultrasound for Improving Skin Ageing, Current Medicinal Chemistry 2025

2025Positive (efficacy)PMID:39171587View source ↗

Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.

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