Shop MEDIHEAL Watermide Moisture Toner Pad (100 count)
Toner
MEDIHEAL

Watermide Moisture Toner Pad (100 count)

~$16· 100 count
RednessDrynessRadiance

Tracked ingredients

Key actives from our research database. Click any to read the full evidence dossier.

Evidence behind the ingredients

Real citations from our research database — one per tracked active in this product. Click any ingredient name to read its full evidence dossier.

AllantoinModerate evidence6 citations

A gentle smoother and skin-soother. Reduces flakiness and helps the surface look more even.

Xu Z et al., Efficacy and Safety of Topical Compound Heparin Sodium Allantoin Gel for the Treatment of Rosacea, Journal of Cosmetic Dermatology 2025;24(4):e70129 — RCT (n=82, 12 weeks): allantoin gel improved erythema and alleviated itching/burning vs traditional therapy

2025Positive — efficacyPMID:40177799View source ↗

Tan C et al., The combination of allantoin, bisabolol, D-panthenol and dipotassium glycyrrhizinate mitigates UVB-induced PGE2 synthesis by keratinocytes, International Journal of Cosmetic Science 2024;46(5):691-701 — in vitro: allantoin combination reduced UVB-induced PGE2, IL-1α, IL-6, IL-8, TNFα

2024Mechanism onlyPMID:38433250View source ↗

Saucedo-Acuna RA et al. (Mexico), Characterization and In Vivo Assay of Allantoin-Enriched Pectin Hydrogel for the Treatment of Skin Wounds, International Journal of Molecular Sciences 2023;24(8):7377 — allantoin-pectin hydrogel reduced wound healing time by ~71% with complete closure at day 15 in rat model

2023Mechanism onlyPMID:37108540View source ↗
Sodium PCAModerate evidence4 citations

Replenishes one of the actual humectant molecules your own skin makes. Levels drop in eczema and with age, so topping it up genuinely helps dry, dehydrated, or atopic-prone skin feel less tight.

Novel design of pyrrolidonecarboxylic acid and sodium dilauramidoglutamide lysine complex for targeted drug delivery to human stratum corneum, International Journal of Pharmaceutics 2025

2025Mechanism onlyPMID:40187708View source ↗

Baldwin H, Del Rosso J, Going Beyond Ceramides in Moisturizers: The Role of Natural Moisturizing Factors, Journal of Drugs in Dermatology 2024 — review establishing PCA (pyrrolidone carboxylic acid) as a core skin natural moisturizing factor alongside amino acids, urea, lactate, and electrolytes; essential to barrier function and xerosis treatment

2024Mechanism onlyPMID:38834224View source ↗

Li L et al., Association Between Skin Acid Mantle, Natural Moisturizing Factors, and Antibacterial Activity Against S. aureus in the Stratum Corneum, Clinical Cosmetic and Investigational Dermatology 2023 — PCA and urocanic acid as NMF components contribute to skin antibacterial defense; 1-unit pH drop = 68.1% S. aureus cell death

2023Mechanism onlyPMID:37378303View source ↗
Lactobacillus FermentAnecdotal evidence4 citations

A "postbiotic" (dead probiotic bits) that talks to your skin microbiome without adding live bugs. Patches up a leaky barrier and is friendly even on very reactive skin.

Algieri F, Pimazzoni S et al. (Italy), Postbiotic derived from Lacticaseibacillus paracasei CNCM I-5220 as a novel approach to improve ageing-induced skin damage, Scientific Reports 2026 — 6-week topical postbiotic application reduced roughness and increased hydration, elasticity, and echogenicity vs placebo; boosted hyaluronic acid in keratinocytes and pro-collagen in fibroblasts

2026Positive — efficacyPMID:42168426View source ↗

Flores Rodriguez JC et al. (Mexico/Colombia/Costa Rica), Postbiotics in Dermatology: A Literature Review of Emerging Topical Therapies for Acne, Rosacea, and Eczema, Cureus 2026;18(3) — review of 16 studies: postbiotics improved SCORAD and barrier function in atopic dermatitis; reduced inflammatory acne lesions 50-70% and suppressed sebum 42-72%

2026Meta-analysis — positivePMID:42005241View source ↗

Effects of a lotion containing probiotic ferment lysate as the main functional ingredient on enhancing skin barrier: a randomized, self-control study, Scientific Reports 2023

2023Positive — efficacyPMID:37803101View source ↗

Sources: PubMed · KCI · J-Stage · CNKI · Wanfang · SFD · MFDS · Cochrane · SCCS · CIR. Every entry points to a specific document. See methodology for what each outcome label means.

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