No.1 Pantothenic B5 Active Soothing Cream
What it's good for
Key actives from our research database. Click any to read the full evidence dossier.
Refills the natural barrier between your skin cells. Locks moisture in, keeps irritants out, calms dry or damaged skin.
Good for: Barrier repair
Evidence behind the ingredients
Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.
Refills the natural barrier between your skin cells. Locks moisture in, keeps irritants out, calms dry or damaged skin.
Andrew PV et al., Topical supplementation with physiological lipids rebalances the stratum corneum ceramide profile and strengthens skin barrier function in adults predisposed to atopic dermatitis, British Journal of Dermatology 2025;193(4):729-740 — physiological-lipid emulsion raised SC ceramide NP/AP and improved barrier function vs control
Nugroho WT, Sawitri, Astindari, Utomo B, Listiawan MY, Ervianti E, Astari L. The Efficacy of Moisturisers Containing Ceramide Compared with Other Moisturisers in the Management of Atopic Dermatitis: A Systematic Literature Review and Meta-Analysis. Indian J Dermatol. 2023;68(1):53-58. — Meta-analysis of 5 studies found ceramide-containing moisturisers produced significantly greater improvement in SCORAD compared with non-ceramide moisturisers in atopic dermatitis.
Shindo S et al., Effects of a moisturizer containing pseudo-ceramide and a eucalyptus extract on sweating function in adult atopic dermatitis: a double-blind, randomized, controlled left-right comparison clinical trial, Journal of Cosmetic Dermatology 2022;21(10):4503-4509 — pseudo-ceramide + eucalyptus moisturizer restored sweating function and barrier in AD adults
Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.
Full ingredient list
Everything on the package label, not just the tracked actives above.
- Contains silicones: Vinyl Dimethicone, Caprylyl Methicone, DimethiconolNo irritancy evidence. CIR rates this safe as used; some shoppers avoid it by preference.
+−Show all 59 ingredients
Listed in the order printed on the package. By regulation, ingredients at 1% or higher are listed in descending order by concentration, so the first entry is the largest part of the formula.
- Water
- Butylene Glycol
- Glycerin
- Niacinamide
- Cetyl Ethylhexanoate
- Dicaprylyl Carbonate
- 1,2-Hexanediol
- Pentylene Glycol
- Vinyl Dimethicone
- Centella Asiatica Extract
- Chlorella Vulgaris Extract
- Sophora Angustifolia Root Extract
- Melia Azadirachta Leaf Extract
- Melia Azadirachta Flower Extract
- Coccinia Indica Fruit Extract
- Ocimum Sanctum Leaf Extract
- Curcuma Longa (Turmeric) Root Extract
- Aloe Barbadensis Flower Extract
- Solanum Melongena (Eggplant) Fruit Extract
- Corallina Officinalis Extract
- Camellia Sinensis Leaf Extract
- Centella Asiatica Leaf Extract
- Cladosiphon Okamuranus Extract
- White Willow Bark Extract
- Houttuynia Cordata Extract
- Coffea Arabica (Coffee) Seed Extract
- Citrus Aurantium Bergamia (Bergamot) Leaf Extract
- Pinus Densiflora Leaf Extract
- Alpha- Arbutin
- Argania Spinosa Kernel Oil
- Sesamum Indicum (Sesame) Seed Oil
- Serenoa Serrulata Fruit Extract
- Glycyrrhiza Glabra (Licorice) Extract
- Caprylyl Methicone
- Erythritol
- Panthenol
- Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
- Dimethiconol
- Polymethylsilsesquioxane
- Acrylates/C10-30 Alkyl Acrylate Crosspolymer
- Glucose
- Tromethamine
- Silica
- Fructooligosaccharides
- Fructose
- Ethylhexylglycerin
- Sodium Phytate
- Glyceryl Acrylate/Acrylic Acid Copolymer
- Caprylic/Capric Triglyceride
- Hydrogenated Lecithin
- Tocopherol
- Decyl Glucoside
- Pantothenic Acid
- Polyglyceryl-4 Caprate
- Polyglyceryl-6 Caprylate
- Zinc Pca
- Methyl Diisopropyl Propionamide
- Beta-Sitosterol
- Xanthan Gum
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