Mulberry Extract for Melasma
A "natural skin lightener" with actual clinical-trial backing for melasma. A placebo-controlled study showed real MASI improvement. Sits well alongside vitamin C, alpha-arbutin, or niacinamide in a brightening stack.
Why it works for Melasma
Fades patches by slowing pigment production, thanks to natural compounds in white mulberry root (mulberroside and oxyresveratrol). In a placebo-controlled trial, a 75% mulberry extract oil meaningfully lowered melasma scores at 8 weeks (from 4.08 to 2.88), while placebo barely changed.
How Mulberry Extract works
Mulberroside-, oxyresveratrol-, and kuwanon-rich Moraceae extract that competitively inhibits tyrosinase and downregulates melanogenic gene expression in melanocytes; clinically reduced MASI scores in a placebo-controlled melasma trial.
Evidence
2 citations from our ingredient database. Full citation list on the Mulberry Extract ingredient page.