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Ingredients Barrier repair Squalane
15Sq
Sourced from olives + sugarcane
Tier · Anecdotal evidence
Barrier repair · Hydrating

Squalane

INCI: Squalane · Also called: Hydrogenated Squalene

A lightweight oil that mimics what your skin already makes. Softens and seals in hydration without feeling greasy.

For your skin

A lightweight oil that mimics what your skin already makes. Softens and seals in hydration without feeling greasy.

Want the science? Keep reading ↓

Mechanism of action

Stable saturated lipid that mimics skin sebum; reinforces the barrier without oxidizing.

Why we tier this anecdotal

5 cited papers across 2 countries. Most of what's cited here is mechanism-level or in-vitro work. We track this as Anecdotal until controlled clinical trials accumulate.

4
International
1
United States

Layering matrix

Compare with

Cited research

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Wolosik K et al., Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast, Molecules 2025;30(9):1964 — low-dose squalane (0.005-0.015%) restored collagen biosynthesis and wound healing in UVA-exposed human dermal fibroblasts

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Morgan AB et al., Explicating the multifunctional roles of tocotrienol and squalene in promoting skin health, Skin Health and Disease 2024;4(5):e448 — squalene/squalane promotes skin health via antioxidant, hydrating, emollient, anti-inflammatory mechanisms

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Fiume M et al., Safety Assessment of Squalane and Squalene as Used in Cosmetics, International Journal of Toxicology 2023;42(3_suppl):107S-109S — CIR expert-panel assessment concluding squalane is safe as a cosmetic ingredient

2023Safety assessmentPMID:37752766View source ↗
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Kim SK, Karadeniz F, Biological importance and applications of squalene and squalane, Advances in Food and Nutrition Research 2012;65:223-233 — comprehensive review of squalene/squalane bioactivity supporting nutraceutical, pharmaceutical, and cosmetic applications

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Huang ZR et al., Biological and pharmacological activities of squalene and related compounds: potential uses in cosmetic dermatology, Molecules 2009;14(1):540-54

Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.