Shop ma:nyo Pure Cleansing Oil Natural Oil Cleanser 200ml
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Pure Cleansing Oil Natural Oil Cleanser 200ml

~$14· 200ml
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Evidence behind the ingredients

Real citations from our research database — one per tracked active in this product. Click any ingredient name to read its full evidence dossier.

SqualaneModerate evidence7 citations

A lightweight oil that mimics what your skin already makes. Softens and seals in hydration without feeling greasy.

Wolosik K et al., Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast, Molecules 2025;30(9):1964 — low-dose squalane (0.005-0.015%) restored collagen biosynthesis and wound healing in UVA-exposed human dermal fibroblasts

2025Mechanism onlyPMID:40363772View source ↗

Morgan AB et al., Explicating the multifunctional roles of tocotrienol and squalene in promoting skin health, Skin Health and Disease 2024;4(5):e448 — squalene/squalane promotes skin health via antioxidant, hydrating, emollient, anti-inflammatory mechanisms

2024Mechanism onlyPMID:39355739View source ↗

Prakoeswa CRS et al. (Indonesia), The Role of Moisturizer Containing Anti-inflammatory on Skin Hydration in Mild-Moderate Atopic Dermatitis Patients, Dermatology Research and Practice 2024;2024:3586393 — multi-ingredient anti-inflammatory moisturizer (shea butter + bacterial lysate + allantoin + bisabolol + botanicals + squalane as one emollient among many) improved skin hydration over 14 days vs standard in AD patients. NOTE: result cannot be attributed to squalane alone

2024Positive — efficacyPMID:39741562View source ↗
Camellia OilModerate evidence7 citations

A lightweight Japanese plant oil that hydrates and seals in moisture without feeling heavy.

Jiao Y et al., Restorative effects of camellia oil on the skin-barrier function in a model of DNCB-induced atopic dermatitis, European Journal of Histochemistry 2025;69(1):4147 — topical camellia oil improved AD symptoms, upregulated filaggrin, reduced inflammatory infiltration in mouse model

2025Positive — efficacyPMID:39836107View source ↗

Lin TK et al., Anti-inflammatory and skin barrier repair effects of topical application of some plant oils, International Journal of Molecular Sciences 2017;19(1):70

2017Positive — efficacyPMID:29280987View source ↗

Chaikul P et al., Melanogenesis Inhibitory and Antioxidant Effects of Camellia oleifera Seed Oil, Advanced Pharmaceutical Bulletin 2017;7(3):473-477 — camellia oil demonstrated tyrosinase inhibition, reduced melanin content, antioxidant cellular protection

2017Positive — efficacyPMID:29071231View source ↗
Jojoba OilModerate evidence2 citations

Technically a wax that masquerades as oil, molecularly closer to your own sebum than any other plant oil. Hydrates without clogging pores, calms inflammation, and plays well in acne-prone and sensitive routines.

Blaak J, Staib P, An updated review on efficacy and benefits of sweet almond, evening primrose and jojoba oils in skin care applications, International Journal of Cosmetic Science 2022;44(1):1-9 — jojoba oil documented as effective for strengthening stratum corneum integrity, recovery, and lipid ratio

2022Meta-analysis — positivePMID:34957578View source ↗

Lin TK, Zhong L, Santiago JL, Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils, International Journal of Molecular Sciences 2017;19(1):70 — jojoba reviewed among 19 plant oils: supports stratum-corneum lipid replenishment, anti-inflammatory and wound-healing effects

2017Mechanism onlyPMID:29280987View source ↗
+3 more ingredients
Argan OilModerate evidence2 citations

The Moroccan kitchen-staple oil with real cosmetic data behind it. Daily use measurably improves skin elasticity in postmenopausal women. Good for dry, mature, or barrier-compromised skin without feeling greasy.

Lin TK, Zhong L, Santiago JL, Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils, International Journal of Molecular Sciences 2017;19(1):70 — review of 19 plant oils including argan: documents anti-inflammatory, antioxidant, stratum-corneum barrier-repair mechanisms

2017Mechanism onlyPMID:29280987View source ↗

Boucetta KQ et al., The effect of dietary and/or cosmetic argan oil on postmenopausal skin elasticity, Clinical Interventions in Aging 2015;10:339-349 — 60-day RCT: both dietary and topical argan oil significantly increased cutometer-measured gross, net, and biological elasticity (all p<0.001) vs olive oil control

2015Positive — efficacyPMID:25673976View source ↗
EGCG (Green Tea)Strong evidence7 citations

A polyphenol from green tea that calms UV-triggered redness and reinforces your sunscreen as a second line of antioxidant defense.

Detudom P, Kamanamool N, Paichitrojjana A, Udompataikul P, Udompataikul M, Efficacy of anti-sebum moisturizing cream containing 2% l-carnitine and 5% epigallocatechin gallate in seborrhea, Journal of Cosmetic Dermatology 2023;22(11):3058-3064 — Thai RCT showed EGCG-containing cream significantly reduced sebum and improved hydration in seborrhea

2023Positive — efficacyPMID:37194909View source ↗

Ud-Din S et al., A Double-Blind, Randomized Trial Shows the Role of Zonal Priming and Direct Topical Application of Epigallocatechin-3-Gallate in the Modulation of Cutaneous Scarring in Human Skin, Journal of Investigative Dermatology 2019;139(8):1680-1690 — topical EGCG reduced scar thickness weeks 1-3 and increased elasticity at week 4 vs placebo

2019Positive — efficacyPMID:30822414View source ↗

Shin S et al., Epigallocatechin Gallate-Mediated Alteration of the MicroRNA Expression Profile in DHT-Treated Human Dermal Papilla Cells, Annals of Dermatology 2016;28(3):327-34 — EGCG altered miRNA expression to protect dermal papilla cells from DHT-induced death, oxidative stress, and senescence (hair-loss mechanism)

2016Mechanism onlyPMID:27274631View source ↗
Rice Bran ExtractModerate evidence8 citations

A traditional Japanese brightener with built-in antioxidants. Softens, hydrates, and adds glow.

Syafitri E et al., Cutaneous Delivery of Bioactive Components from a Rice Bran Oil Nanoemulsion and Their Biodistribution in Porcine and Human Skin, International Journal of Pharmaceutics: X 2026

2026Mechanism onlyPMID:42028061View source ↗

Zamil DH et al., Dermatological uses of rice products: Trend or true?, Journal of Cosmetic Dermatology 2022;21(11):6056-6060 — review of rice-derived ingredients with antiaging, anti-inflammatory, brightening, photoprotective effects

2022Mechanism onlyPMID:35587098View source ↗

Miyasaka K et al., Anti-melanogenic effects of glucosylceramides and elasticamide derived from rice oil by-products in melanoma cells, melanocytes, and human skin, Journal of Food Biochemistry 2022;46(10):e14353 — rice-derived ceramides/elasticamide suppressed UV-induced pigmentation

2022Positive — efficacyPMID:35986572View source ↗

Sources: PubMed · KCI · J-Stage · CNKI · Wanfang · SFD · MFDS · Cochrane · SCCS · CIR. Every entry points to a specific document. See methodology for what each outcome label means.

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