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Shop Mary&May Houttuynia Cordata + Tea Tree Serum 1.01 fl oz
Serum
Mary&May

Houttuynia Cordata + Tea Tree Serum 1.01 fl oz

~$18· 1.01 fl oz
AcneRednessVisible pores

What it's good for

Key actives from our research database. Click any to read the full evidence dossier.

  • HeartleafModerate evidenceFull dossier ↗

    A calming K-beauty botanical that's also antibacterial, so it pairs well for acne-prone, sensitive skin.

    Good for: Anti-inflammatory, Anti-acne

  • Tea Tree OilModerate evidenceFull dossier ↗

    A natural acne spot-treatment that kills the bacteria behind red, painful pimples. Slower than benzoyl peroxide but with fewer side effects when used at 5%.

    Good for: Anti-acne, Anti-inflammatory

Evidence behind the ingredients

Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.

HeartleafModerate evidence8 citations

A calming K-beauty botanical that's also antibacterial, so it pairs well for acne-prone, sensitive skin.

Song Z et al., Inhibition of LPS-Induced Skin Inflammatory Response and Barrier Damage via MAPK/NF-kB Signaling Pathway by Houttuynia cordata Thunb Fermentation Broth, Foods 2024

2024Mechanism onlyPMID:38790770View source ↗

Kwon N et al., Protective Effects of Fermented Houttuynia cordata Against UVA and H2O2-Induced Oxidative Stress in Human Skin Keratinocytes, Applied Biochemistry and Biotechnology 2023;195(5):3027-3046 — Korean-authored; fermented H. cordata showed antioxidant and anti-inflammatory protection against UVA/H2O2 stress

2023Mechanism onlyPMID:36495375View source ↗

Rafiq S et al., Pharmacological Effects of Houttuynia cordata Thunb (H. cordata): A Comprehensive Review, Pharmaceuticals (Basel) 2022

2022Mechanism onlyPMID:36145299View source ↗
Tea Tree OilModerate evidence6 citations

A natural acne spot-treatment that kills the bacteria behind red, painful pimples. Slower than benzoyl peroxide but with fewer side effects when used at 5%.

Najafi-Taher R et al., A topical gel of tea tree oil nanoemulsion containing adapalene versus adapalene marketed gel in patients with acne vulgaris: a randomized clinical trial, Archives of Dermatological Research 2022;314(7):673-679 — RCT showed tea tree oil + adapalene nanoemulsion gel produced significantly better reduction in total, inflammatory and non-inflammatory acne lesions than standard adapalene

2022Positive (efficacy)PMID:34251536View source ↗

Zambello A et al. Tea tree oil contact sensitization in children. Contact Dermatitis. 2021;84(2):123-124. doi:10.1111/cod.13699 — Documents allergic contact dermatitis from tea tree oil exposure in pediatric patients identified through patch testing; highlights sensitization risk in children.

2021Safety assessmentPMID:32885466View source ↗

Malhi HK, Tu J, Riley TV, Kumarasinghe SP, Hammer KA, Tea tree oil gel for mild to moderate acne; a 12 week uncontrolled, open-label phase II pilot study, Australasian Journal of Dermatology 2017;58(3):205-210

2017Positive (efficacy)PMID:27000386View source ↗

Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.

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