TXA Niacinamide Capsule Cream
What it's good for
Key actives from our research database. Click any to read the full evidence dossier.
A multitasker that calms redness, evens out skin tone, and helps oily skin balance out. One of the safest do-a-little-of-everything ingredients.
Good for: Brightening, Barrier repair, Anti-inflammatory
A pure hydrator that holds water in your skin. Makes skin look plumper and smoother almost immediately.
Good for: Hydrating
Refills the natural barrier between your skin cells. Locks moisture in, keeps irritants out, calms dry or damaged skin.
Good for: Barrier repair
Fades stubborn dark patches like melasma and deep marks left behind by acne or hormonal shifts. The one to reach for when other brighteners haven't worked.
Good for: Brightening
A safer, slower-acting alternative to prescription-strength dark-spot faders. Built for long-term use without irritation.
Good for: Brightening
A "master antioxidant" your body already makes. In skincare it gently lightens overall tone and helps fade pigmentation when used consistently over months.
Good for: Brightening, Antioxidant
Evidence behind the ingredients
Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.
A multitasker that calms redness, evens out skin tone, and helps oily skin balance out. One of the safest do-a-little-of-everything ingredients.
Moro F et al., Skin Cancer Prevention and Antiaging: Role of Nicotinamide, International Journal of Molecular Sciences 2026
Passeron T et al., An Investigator-Blinded, Randomized Trial of a Broad-Spectrum Sunscreen Containing Sclareolide and Niacinamide, Dermatology and Therapy (Heidelberg) 2026
Vergilio MM et al., Topical Formulation with Niacinamide Combined with 5 MHz Ultrasound for Improving Skin Ageing, Current Medicinal Chemistry 2025
A pure hydrator that holds water in your skin. Makes skin look plumper and smoother almost immediately.
Karabat MU, Tuncer MC. Effects of hyaluronic acid on skin at the cellular level: a systematic review. Rev Assoc Med Bras. 2025;71(8):e20250208. — Systematic review of 45 studies found low-molecular-weight HA stimulates keratinocyte proliferation and migration while high-molecular-weight HA drives skin hydration, supporting topical HA as an effective skin-hydrating and barrier-supporting ingredient.
Bravo B et al., Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence, Dermatology and Therapy 2022;12(12):2657-2680 — HA-based cosmeceuticals reliably improve hydration and signs of skin aging
Lee SG et al., Hyaluronan Oligosaccharides Improve Rosacea-Like Phenotype through Anti-Inflammatory and Epidermal Barrier-Improving Effects, Annals of Dermatology 2020
Refills the natural barrier between your skin cells. Locks moisture in, keeps irritants out, calms dry or damaged skin.
Andrew PV et al., Topical supplementation with physiological lipids rebalances the stratum corneum ceramide profile and strengthens skin barrier function in adults predisposed to atopic dermatitis, British Journal of Dermatology 2025;193(4):729-740 — physiological-lipid emulsion raised SC ceramide NP/AP and improved barrier function vs control
Nugroho WT, Sawitri, Astindari, Utomo B, Listiawan MY, Ervianti E, Astari L. The Efficacy of Moisturisers Containing Ceramide Compared with Other Moisturisers in the Management of Atopic Dermatitis: A Systematic Literature Review and Meta-Analysis. Indian J Dermatol. 2023;68(1):53-58. — Meta-analysis of 5 studies found ceramide-containing moisturisers produced significantly greater improvement in SCORAD compared with non-ceramide moisturisers in atopic dermatitis.
Shindo S et al., Effects of a moisturizer containing pseudo-ceramide and a eucalyptus extract on sweating function in adult atopic dermatitis: a double-blind, randomized, controlled left-right comparison clinical trial, Journal of Cosmetic Dermatology 2022;21(10):4503-4509 — pseudo-ceramide + eucalyptus moisturizer restored sweating function and barrier in AD adults
+−3 more ingredients
Fades stubborn dark patches like melasma and deep marks left behind by acne or hormonal shifts. The one to reach for when other brighteners haven't worked.
Liang Y et al., Comparative efficacy and safety of tranexamic acid for melasma by different administration methods: A systematic review and network meta-analysis, Journal of Cosmetic Dermatology 2024 — oral TXA + topical agents most effective delivery route
Tranexamic Acid Ameliorates Skin Hyperpigmentation by Downregulating Endothelin-1 Expression in Dermal Microvascular Endothelial Cells, Annals of Dermatology 2024;36(3):151-162 — mechanism study showing oral TXA suppresses endothelin-1 in vascular endothelial cells
Calacattawi R, Alshahrani M, Aleid M et al., Tranexamic acid as a therapeutic option for melasma management: a meta-analysis and systematic review of randomized controlled trials, Journal of Dermatological Treatment 2024;35(1):2361106 — pooled RCT evidence that tranexamic acid significantly reduces melasma severity via plasmin-inhibition of UV-triggered melanogenesis
A safer, slower-acting alternative to prescription-strength dark-spot faders. Built for long-term use without irritation.
Ma ZY, Lu Y, Melanin synthesis and regulation in vivo and commonly used melanin inhibitors from natural products and traditional Chinese medicine, Zhongguo Zhong Yao Za Zhi (China Journal of Chinese Materia Medica) 2020;45(24):5898-5916 — Beijing University of Chinese Medicine review classifies arbutin among tyrosinase-active-site-targeting melanin inhibitors
Morag M et al., A double-blind, placebo-controlled randomized trial of Serratulae quinquefoliae folium, a new source of β-arbutin, in selected skin hyperpigmentations, Journal of Cosmetic Dermatology 2015 — 76% of melasma patients showed clinical lightening over 8 weeks
Kim H, Choi HR, Kim DS, Park KC, Topical hypopigmenting agents for pigmentary disorders and their mechanisms of action, Annals of Dermatology 2012;24(1):1-6 — review classifies arbutin among hypopigmenting agents via tyrosinase regulation as a hydroquinone alternative
A "master antioxidant" your body already makes. In skincare it gently lightens overall tone and helps fade pigmentation when used consistently over months.
Stanescu C et al., Glutathione in Skin Aging and Tissue Regeneration: A Systematic Review of Molecular Mechanisms, Redox Modulation, and Biomedical Implications, Molecules 2026
Sarkar R et al., Glutathione as a skin-lightening agent and in melasma: a systematic review, International Journal of Dermatology 2025
Wahab S et al., Combination of topical and oral glutathione as a skin-whitening agent: a double-blind randomized controlled clinical trial, International Journal of Dermatology 2021;60(8):1013-1018 — 8-week RCT showed combination significantly lowered melanin and raised lightness vs placebo
Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.
Full ingredient list
Everything on the package label, not just the tracked actives above.
- Contains silicones: SimethiconeNo irritancy evidence. CIR rates this safe as used; some shoppers avoid it by preference.
+−Show all 62 ingredients
Listed in the order printed on the package. By regulation, ingredients at 1% or higher are listed in descending order by concentration, so the first entry is the largest part of the formula.
- Water
- Glycerin
- Niacinamide (50,000 Ppm)
- Methylpropanediol
- Propanediol
- 1,2-Hexanediol
- Dipropylene Glycol
- Caprylic/Capric Triglyceride
- Glyceryl Glucoside
- Butylene Glycol
- Arginine
- Ethylhexyl Palmitate
- Carbomer
- Cetearyl Alcohol
- Cetearyl Olivate
- Sorbitan Olivate
- C12-14 Alketh-12
- Ammonium Acryloyldimethyltaurate/VP Copolymer
- Simethicone
- Ethylhexylglycerin
- Melia Azadirachta Flower Extract
- Melia Azadirachta Leaf Extract
- Adenosine
- Polyacrylate-13
- Disodium EDTA
- Cyanocobalamin
- Triethyl Citrate
- Betaine
- Polyisobutene
- Glyceryl Stearate
- Hydrolyzed Sclerotium Gum
- Tranexamic Acid
- Abelmoschus Esculentus (Okra) Fruit Extract
- Panthenol
- Coccinia Indica Fruit Extract
- Corallina Officinalis Extract
- Polysorbate 20
- Sorbitan Isostearate
- Glutathione
- Fragaria Vesca (Strawberry) Fruit Extract
- Castanea Crenata (Chestnut) Shell Extract
- Citrus Junos Peel Extract
- Betula Platyphylla Japonica Bark Extract
- Ricinus Communis (Castor) Seed Oil
- Bisabolol
- Ferulic Acid
- Cymbopogon Citratus Leaf Oil
- Illicium Verum (Anise) Fruit/Seed Oil
- Octyldodecanol
- Hydrolyzed Hyaluronic Acid
- 3-0-Ethyl Ascorbic Acid
- Sodium Hyaluronate
- Alpha-Arbutin
- Hydrogenated Lecithin
- Ceramide NP
- Hydroxypropyltrimonium Hyaluronate
- Caprylyl Glycol
- Sodium Acetylated Hyaluronate
- Hyaluronic Acid
- Sodium Hyaluronate Crosspolymer
- Hydrolyzed Sodium Hyaluronate
- Potassium Hyaluronate
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