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Ingredients Hydrating Glycerin
46Gc
Sourced from lab
Tier · Moderate evidence
Hydrating

Glycerin

INCI: Glycerin · Also called: Glycerol, Glycerine

A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.

For your skin

A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.

Want the science? Keep reading ↓

Mechanism of action

Trihydric alcohol humectant that pulls water from the dermis and atmosphere into the stratum corneum.

Why we tier this moderate

6 cited papers across 2 countries. The mechanism is well-described and there's at least one controlled trial in the literature, but we tier this Moderate rather than Strong to stay honest about how many specific papers we cite directly.

4
International
2
European Union

Layering matrix

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Cited research

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Danby SG et al., Different types of emollient cream exhibit diverse physiological effects on the skin barrier in adults with atopic dermatitis, Clinical and Experimental Dermatology 2022;47(6):1154-1164 — glycerol+urea emollient delivered superior barrier-strengthening and irritant protection

2022Positive (efficacy)PMID:35167133View source ↗
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Youssef R et al., Glycerol 85% efficacy on atopic skin and its microbiome: a randomized controlled trial, Journal of Dermatological Treatment 2021;32(7):730-736 — topical glycerol 85% RCT on atopic skin

2021Positive (efficacy)PMID:31869257View source ↗
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Evans NJ et al., Human axillary skin condition is improved following incorporation of glycerol into the stratum corneum from an antiperspirant formulation, Archives of Dermatological Research 2017;309(9):739-748 — 4% glycerol penetrated axillary SC, reduced irritation, improved hydration

2017Positive (efficacy)PMID:28889318View source ↗
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Lindh JD, Bradley M, Clinical Effectiveness of Moisturizers in Atopic Dermatitis and Related Disorders: A Systematic Review, American Journal of Clinical Dermatology 2015;16(5):341-359 — SR of emollients incl. glycerol for TEWL and stratum corneum hydration

2015Meta-analysis (positive)PMID:26267423View source ↗
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Breternitz M et al., Placebo-controlled, double-blind, randomized, prospective study of a glycerol-based emollient on eczematous skin in atopic dermatitis, Skin Pharmacology and Physiology 2008;21(1):39-45 — topical 20% glycerol vs vehicle improved eczematous skin

2008Positive (efficacy)PMID:18025807View source ↗
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Loden M, Role of topical emollients and moisturizers in the treatment of dry skin barrier disorders, American Journal of Clinical Dermatology 2003;4(11):771-88

2003Positive (efficacy)PMID:14572299View source ↗

Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.