Shop Anessa Perfect UV Sunscreen Skincare Milk SPF50+ PA++++ 60ml
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Anessa

Perfect UV Sunscreen Skincare Milk SPF50+ PA++++ 60ml

~$18· 60mlSPF 50
RednessDrynessRadiance

Evidence behind the ingredients

Real citations from our research database — one per tracked active in this product. Click any ingredient name to read its full evidence dossier.

Hyaluronic AcidStrong evidence7 citations

A pure hydrator that holds water in your skin. Makes skin look plumper and smoother almost immediately.

Bravo B et al., Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence, Dermatology and Therapy 2022;12(12):2657-2680 — HA-based cosmeceuticals reliably improve hydration and signs of skin aging

2022Meta-analysis — positivePMID:36200921View source ↗

Lee SG et al., Hyaluronan Oligosaccharides Improve Rosacea-Like Phenotype through Anti-Inflammatory and Epidermal Barrier-Improving Effects, Annals of Dermatology 2020

2020Mechanism onlyPMID:33911737View source ↗

An JH et al., Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin, Annals of Dermatology 2019;31(3):263-271 — cross-linked HA microneedle patches improved wrinkles on Korean skin with minimal discomfort

2019Positive — efficacyPMID:33911590View source ↗
Vitamin EModerate evidence6 citations

A workhorse antioxidant that defends your skin from daily oxidative damage. Pairs especially well with vitamin C, and it's in nearly every good moisturizer for a reason.

Neves JR et al., Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs, Journal of Cosmetic Dermatology 2022;21(10):4462-4469 — tocopherol-containing antioxidant serum reduced pollution-induced damage and improved aging signs

2022Positive — efficacyPMID:35150043View source ↗

Warshaw EM et al., Patch Testing With Tocopherol and Tocopherol Acetate: The North American Contact Dermatitis Group Experience, 2001 to 2016, Dermatitis 2021;32(5):308-318 — 15-year NACDG data: positive patch-test reactions to tocopherol rare given widespread cosmetic use

2021Safety assessmentPMID:34238818View source ↗

Lin FH et al., Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin, Journal of Investigative Dermatology 2005;125(4):826-832 — ferulic acid + vit C + vit E combo doubled photoprotection vs C+E alone (cross-listed; same paper cited for Ferulic Acid and Vit C)

2005Positive — efficacyPMID:16185284View source ↗
EGCG (Green Tea)Strong evidence7 citations

A polyphenol from green tea that calms UV-triggered redness and reinforces your sunscreen as a second line of antioxidant defense.

Detudom P, Kamanamool N, Paichitrojjana A, Udompataikul P, Udompataikul M, Efficacy of anti-sebum moisturizing cream containing 2% l-carnitine and 5% epigallocatechin gallate in seborrhea, Journal of Cosmetic Dermatology 2023;22(11):3058-3064 — Thai RCT showed EGCG-containing cream significantly reduced sebum and improved hydration in seborrhea

2023Positive — efficacyPMID:37194909View source ↗

Ud-Din S et al., A Double-Blind, Randomized Trial Shows the Role of Zonal Priming and Direct Topical Application of Epigallocatechin-3-Gallate in the Modulation of Cutaneous Scarring in Human Skin, Journal of Investigative Dermatology 2019;139(8):1680-1690 — topical EGCG reduced scar thickness weeks 1-3 and increased elasticity at week 4 vs placebo

2019Positive — efficacyPMID:30822414View source ↗

Shin S et al., Epigallocatechin Gallate-Mediated Alteration of the MicroRNA Expression Profile in DHT-Treated Human Dermal Papilla Cells, Annals of Dermatology 2016;28(3):327-34 — EGCG altered miRNA expression to protect dermal papilla cells from DHT-induced death, oxidative stress, and senescence (hair-loss mechanism)

2016Mechanism onlyPMID:27274631View source ↗
+3 more ingredients
HoneyModerate evidence3 citations

An ancient antimicrobial that has graduated into modern wound clinics. Cochrane and meta-analytic evidence shows it heals partial-thickness burns ~4-5 days faster than conventional dressings; smaller dermatology trials show it calms atopic dermatitis flares without irritation.

Jull AB, Cullum N, Dumville JC, Westby MJ, Deshpande S, Walker N. Honey as a topical treatment for wounds. Cochrane Database Syst Rev. 2015;(3):CD005083.

2015Meta-analysis — mixedPMID:25742878View source ↗

Mandal MD, Mandal S. Honey: its medicinal property and antibacterial activity. Asian Pac J Trop Biomed. 2011;1(2):154-160.

2011Mechanism onlyPMID:23569748View source ↗

Wijesinghe M, Weatherall M, Perrin K, Beasley R. Honey in the treatment of burns: a systematic review and meta-analysis of its efficacy. N Z Med J. 2009;122(1295):47-60.

2009Meta-analysis — positivePMID:19648986View source ↗
Zinc OxideModerate evidence5 citations

A physical sunscreen that sits on top of your skin and blocks UV. Broad-spectrum and gentle enough for sensitive or rosacea-prone skin.

Kern C et al., Evaluation of an SPF50 Sunscreen Containing Photolyase and Antioxidants for its Anti-Photoaging Properties and Photoprotection, Journal of Drugs in Dermatology 2022;21(5):517-520 — 10.7% zinc oxide SPF50 mineral sunscreen improved photoaging signs over 12 weeks

2022Positive — efficacyPMID:35533024View source ↗

MFDS Approved Functional Cosmetic Active — Zinc Oxide (UV protection / sunscreen). Korean Ministry of Food and Drug Safety, Cosmetic Functional Active Ingredient List — inorganic UV filter approved under the Korean Functional Cosmetics Codex sunscreen category

2020Regulatory approvalMFDS:ZincOxide-SunscreenView source ↗

CIR Safety Assessment of Zinc Salts as Used in Cosmetics (Scott et al.), final report 2018 / re-review 2024 (covers zinc oxide among 27 zinc ingredients)

2018Safety assessmentDOI:10.1177/10915818241227124View source ↗
Titanium DioxideStrong evidence7 citations

Another physical sunscreen that blocks UV. Often paired with zinc oxide for full sun protection.

Polena H et al., Comparison of Visible Light-Protective Tinted Sunscreen to Untinted Sunscreen to Protect Melasma Patients During Summer: A Prospective Randomized Investigator-Blinded Study, Journal of Cosmetic Dermatology 2025;24(10):e70450 — pigmentary titanium dioxide + iron oxide tinted sunscreen significantly improved pigmentation uniformity between melasma-affected and unaffected skin vs untinted (∆L*, ∆ITA°, ∆E significantly reduced; not in untinted group)

2025Positive — efficacyPMID:41014037View source ↗

SCCS Scientific Advice on Titanium Dioxide (TiO2) (CAS/EC 13463-67-7/236-675-5, 1317-70-0/215-280-1, 1317-80-2/215-282-2), SCCS/1661/23

2024Safety assessmentSCCS/1661/23View source ↗

Ezekwe N et al., Evaluation of the protection of sunscreen products against long wavelength ultraviolet A1 and visible light-induced biological effects, Photodermatology, Photoimmunology & Photomedicine 2024;40(1):e12937 — the titanium dioxide 11% + iron oxide tinted product gave statistically significantly less erythema (IGA, Δoxyhemoglobin, Δa*) and less pigmentation at all time points vs unprotected irradiated skin

2024Positive — efficacyPMID:38069506View source ↗

Sources: PubMed · KCI · J-Stage · CNKI · Wanfang · SFD · MFDS · Cochrane · SCCS · CIR. Every entry points to a specific document. See methodology for what each outcome label means.

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