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Shop Anessa Perfect UV Sunscreen Skincare Milk SPF50+ PA++++ 60ml
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Anessa

Perfect UV Sunscreen Skincare Milk SPF50+ PA++++ 60ml

~$18· 60mlSPF 50
RednessDrynessRadiance

What it's good for

Key actives from our research database. Click any to read the full evidence dossier.

  • Hyaluronic AcidStrong evidenceFull dossier ↗

    A pure hydrator that holds water in your skin. Makes skin look plumper and smoother almost immediately.

    Good for: Hydrating

  • Vitamin EModerate evidenceFull dossier ↗

    A workhorse antioxidant that defends your skin from daily oxidative damage. Pairs especially well with vitamin C, and it's in nearly every good moisturizer for a reason.

    Good for: Antioxidant

  • EGCG (Green Tea)Strong evidenceFull dossier ↗

    A polyphenol from green tea that calms UV-triggered redness and reinforces your sunscreen as a second line of antioxidant defense.

    Good for: Antioxidant, Anti-inflammatory, Sun protection

  • HoneyModerate evidenceFull dossier ↗

    An ancient humectant and antimicrobial ingredient with a long research track record. Its sugar matrix and flavonoids help draw in moisture and support skin comfort; formulas pairing honey with beeswax and olive oil have shown improvement in dry, irritation-prone skin in controlled trials.

    Good for: Anti-inflammatory, Anti-acne, Hydrating

  • Zinc OxideModerate evidenceFull dossier ↗

    A physical sunscreen that sits on top of your skin and blocks UV. Broad-spectrum and gentle enough for sensitive or rosacea-prone skin.

    Good for: Sun protection

  • Titanium DioxideStrong evidenceFull dossier ↗

    Another physical sunscreen that blocks UV. Often paired with zinc oxide for full sun protection.

    Good for: Sun protection

Evidence behind the ingredients

Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.

Hyaluronic AcidStrong evidence7 citations

A pure hydrator that holds water in your skin. Makes skin look plumper and smoother almost immediately.

Karabat MU, Tuncer MC. Effects of hyaluronic acid on skin at the cellular level: a systematic review. Rev Assoc Med Bras. 2025;71(8):e20250208. — Systematic review of 45 studies found low-molecular-weight HA stimulates keratinocyte proliferation and migration while high-molecular-weight HA drives skin hydration, supporting topical HA as an effective skin-hydrating and barrier-supporting ingredient.

2025Meta-analysis (positive)PMID:40990743View source ↗

Bravo B et al., Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence, Dermatology and Therapy 2022;12(12):2657-2680 — HA-based cosmeceuticals reliably improve hydration and signs of skin aging

2022Meta-analysis (positive)PMID:36200921View source ↗

Lee SG et al., Hyaluronan Oligosaccharides Improve Rosacea-Like Phenotype through Anti-Inflammatory and Epidermal Barrier-Improving Effects, Annals of Dermatology 2020

2020Mechanism onlyPMID:33911737View source ↗
Vitamin EModerate evidence6 citations

A workhorse antioxidant that defends your skin from daily oxidative damage. Pairs especially well with vitamin C, and it's in nearly every good moisturizer for a reason.

Neves JR et al., Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs, Journal of Cosmetic Dermatology 2022;21(10):4462-4469 — tocopherol-containing antioxidant serum reduced pollution-induced damage and improved aging signs

2022Positive (efficacy)PMID:35150043View source ↗

Warshaw EM et al., Patch Testing With Tocopherol and Tocopherol Acetate: The North American Contact Dermatitis Group Experience, 2001 to 2016, Dermatitis 2021;32(5):308-318 — 15-year NACDG data: positive patch-test reactions to tocopherol rare given widespread cosmetic use

2021Safety assessmentPMID:34238818View source ↗

Lin FH et al., Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin, Journal of Investigative Dermatology 2005;125(4):826-832 — ferulic acid + vit C + vit E combo doubled photoprotection vs C+E alone (cross-listed; same paper cited for Ferulic Acid and Vit C)

2005Positive (efficacy)PMID:16185284View source ↗
EGCG (Green Tea)Strong evidence7 citations

A polyphenol from green tea that calms UV-triggered redness and reinforces your sunscreen as a second line of antioxidant defense.

Detudom P, Kamanamool N, Paichitrojjana A, Udompataikul P, Udompataikul M, Efficacy of anti-sebum moisturizing cream containing 2% l-carnitine and 5% epigallocatechin gallate in seborrhea, Journal of Cosmetic Dermatology 2023;22(11):3058-3064 — Thai RCT showed EGCG-containing cream significantly reduced sebum and improved hydration in seborrhea

2023Positive (efficacy)PMID:37194909View source ↗

Ud-Din S et al., A Double-Blind, Randomized Trial Shows the Role of Zonal Priming and Direct Topical Application of Epigallocatechin-3-Gallate in the Modulation of Cutaneous Scarring in Human Skin, Journal of Investigative Dermatology 2019;139(8):1680-1690 — topical EGCG reduced scar thickness weeks 1-3 and increased elasticity at week 4 vs placebo

2019Positive (efficacy)PMID:30822414View source ↗

Kim YR et al., Clinical Evaluation of a New-Formula Shampoo for Scalp Seborrheic Dermatitis Containing Rosa centifolia + EGCG: A Randomized Double-Blind Controlled Study, Annals of Dermatology 2014;26(6):733-8 — EGCG-containing shampoo matched ketoconazole and zinc pyrithione efficacy; faster erythema response than 1% zinc pyrithione

2014Positive (efficacy)PMID:25473226View source ↗
+3 more ingredients
HoneyModerate evidence5 citations

An ancient humectant and antimicrobial ingredient with a long research track record. Its sugar matrix and flavonoids help draw in moisture and support skin comfort; formulas pairing honey with beeswax and olive oil have shown improvement in dry, irritation-prone skin in controlled trials.

Semprini A, Braithwaite I, Corin A, et al. Randomised controlled trial of topical kanuka honey for the treatment of acne. BMJ Open. 2016 Feb 1;6(2):e009448. — RCT: kanuka honey + antibacterial soap was NOT significantly more effective than antibacterial soap alone for acne; primary endpoint not met.

2016InconclusivePMID:26832428View source ↗

Jull AB, Cullum N, Dumville JC, Westby MJ, Deshpande S, Walker N. Honey as a topical treatment for wounds. Cochrane Database Syst Rev. 2015;(3):CD005083.

2015Meta-analysis (mixed)PMID:25742878View source ↗

Mandal MD, Mandal S. Honey: its medicinal property and antibacterial activity. Asian Pac J Trop Biomed. 2011;1(2):154-160.

2011Mechanism onlyPMID:23569748View source ↗
Zinc OxideModerate evidence5 citations

A physical sunscreen that sits on top of your skin and blocks UV. Broad-spectrum and gentle enough for sensitive or rosacea-prone skin.

Kern C et al., Evaluation of an SPF50 Sunscreen Containing Photolyase and Antioxidants for its Anti-Photoaging Properties and Photoprotection, Journal of Drugs in Dermatology 2022;21(5):517-520 — 10.7% zinc oxide SPF50 mineral sunscreen improved photoaging signs over 12 weeks

2022Positive (efficacy)PMID:35533024View source ↗

Schneider SL, Lim HW. A review of inorganic UV filters zinc oxide and titanium dioxide. Photodermatol Photoimmunol Photomed. 2019;35(6):442-446. — Review confirms ZnO provides broad-spectrum UVA-UVB coverage; concludes zinc oxide sunscreens are safe with minimal percutaneous absorption risk.

2019Meta-analysis (positive)PMID:30444533View source ↗

CIR Safety Assessment of Zinc Salts as Used in Cosmetics (Scott et al.), final report 2018 / re-review 2024 (covers zinc oxide among 27 zinc ingredients)

2018Safety assessmentDOI:10.1177/10915818241227124View source ↗
Titanium DioxideStrong evidence6 citations

Another physical sunscreen that blocks UV. Often paired with zinc oxide for full sun protection.

Polena H et al., Comparison of Visible Light-Protective Tinted Sunscreen to Untinted Sunscreen to Protect Melasma Patients During Summer: A Prospective Randomized Investigator-Blinded Study, Journal of Cosmetic Dermatology 2025;24(10):e70450 — pigmentary titanium dioxide + iron oxide tinted sunscreen significantly improved pigmentation uniformity between melasma-affected and unaffected skin vs untinted (∆L*, ∆ITA°, ∆E significantly reduced; not in untinted group)

2025Positive (efficacy)PMID:41014037View source ↗

SCCS Scientific Advice on Titanium Dioxide (TiO2) (CAS/EC 13463-67-7/236-675-5, 1317-70-0/215-280-1, 1317-80-2/215-282-2), SCCS/1661/23

2024Safety assessmentSCCS/1661/23View source ↗

Ezekwe N et al., Evaluation of the protection of sunscreen products against long wavelength ultraviolet A1 and visible light-induced biological effects, Photodermatology, Photoimmunology & Photomedicine 2024;40(1):e12937 — the titanium dioxide 11% + iron oxide tinted product gave statistically significantly less erythema (IGA, Δoxyhemoglobin, Δa*) and less pigmentation at all time points vs unprotected irradiated skin

2024Positive (efficacy)PMID:38069506View source ↗

Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.

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