The True Cream Moisturizing Bomb
What it's good for
Key actives from our research database. Click any to read the full evidence dossier.
Pro-vitamin B5. Deeply hydrates and helps repair the skin barrier, calming dry or compromised skin.
Good for: Hydrating, Barrier repair
A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.
Good for: Hydrating
A small molecule your skin already makes. Low concentrations deeply hydrate dry skin; higher concentrations soften thick, scaly patches. A workhorse for very dry, rough, or flaky skin.
Good for: Hydrating, Barrier repair, Exfoliating
A botanical with real clinical wins for irritated, post-procedure, or recovering skin, with randomized-trial support behind its soothing reputation. Gentle enough for delicate, easily reactive skin and dry, sensitive patches.
Good for: Anti-inflammatory
A silicone that sits on your skin as an invisible, non-greasy shield. Reduces water loss, protects against irritants (think soap, friction, incontinence), and is FDA-recognised as a skin protectant from 1-30%. The reason your favourite primer feels silky and your barrier cream actually works under makeup.
Good for: Barrier repair, Hydrating
Evidence behind the ingredients
Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.
Pro-vitamin B5. Deeply hydrates and helps repair the skin barrier, calming dry or compromised skin.
Gao Y et al., Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment, Journal of Cosmetic Dermatology 2025;24(7):e70223 — double-blind RCT (n=60): panthenol mask decreased erythema, enhanced hydration, repaired barrier vs saline
Cho YS et al., Use of Dexpanthenol for Atopic Dermatitis-Benefits and Recommendations Based on Current Evidence, Journal of Clinical Medicine 2022;11(14):3943 — Korean-authored review; dexpanthenol improves barrier and reduces severity in mild-to-moderate AD
Heise R et al., Accelerated wound healing with a dexpanthenol-containing ointment after fractional ablative CO2 laser resurfacing of photo-damaged skin in a randomized prospective clinical trial, Cutaneous and Ocular Toxicology 2019;38(3):274-278 — RCT: dexpanthenol significantly faster wound closure vs petroleum jelly post-laser
A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.
Danby SG et al., Different types of emollient cream exhibit diverse physiological effects on the skin barrier in adults with atopic dermatitis, Clinical and Experimental Dermatology 2022;47(6):1154-1164 — glycerol+urea emollient delivered superior barrier-strengthening and irritant protection
Youssef R et al., Glycerol 85% efficacy on atopic skin and its microbiome: a randomized controlled trial, Journal of Dermatological Treatment 2021;32(7):730-736 — topical glycerol 85% RCT on atopic skin
Evans NJ et al., Human axillary skin condition is improved following incorporation of glycerol into the stratum corneum from an antiperspirant formulation, Archives of Dermatological Research 2017;309(9):739-748 — 4% glycerol penetrated axillary SC, reduced irritation, improved hydration
A small molecule your skin already makes. Low concentrations deeply hydrate dry skin; higher concentrations soften thick, scaly patches. A workhorse for very dry, rough, or flaky skin.
Jawed I et al., Effect of topical treatment with urea in ichthyosis, atopic dermatitis, psoriasis, and other skin conditions: a systematic review, Annals of Medicine and Surgery 2025
Treesirichod A et al., The efficacy and safety of 20% urea cream and 10% urea cream in the treatment of acanthosis nigricans in adolescents: a randomized comparative double-blind study, Journal of Cosmetic Dermatology 2022;21(7):2859-2864 — topical urea cream improved acanthosis nigricans
Piquero-Casals J, Morgado-Carrasco D, Granger C, Trullas C, Jesus-Silva A, Krutmann J, Urea in Dermatology: A Review of its Emollient, Moisturizing, Keratolytic, Skin Barrier Enhancing and Antimicrobial Properties, Dermatology and Therapy (Heidelberg) 2021;11(6):1905-1915
+−2 more ingredients
A botanical with real clinical wins for irritated, post-procedure, or recovering skin, with randomized-trial support behind its soothing reputation. Gentle enough for delicate, easily reactive skin and dry, sensitive patches.
Deligiannidou GE et al. (Greece), An Update of Phytotherapeutic Advances of Marigold (Calendula officinalis L.) in Wound Healing, Plants (Basel) 2025 — peer-reviewed review of 2020-2025 experimental and clinical evidence on Calendula formulations for skin regeneration: healing rate, cell proliferation, inflammatory modulation
Effect of oral Calendula officinalis on second-degree burn wound healing (Iran), Scars Burns and Healing 2023
Siddiquee S et al., Efficacy of topical Calendula officinalis on prevalence of radiation-induced dermatitis: A randomised controlled trial, Australasian Journal of Dermatology 2021;62(1):e35-e40 — topical calendula reduced radiation-induced dermatitis
A silicone that sits on your skin as an invisible, non-greasy shield. Reduces water loss, protects against irritants (think soap, friction, incontinence), and is FDA-recognised as a skin protectant from 1-30%. The reason your favourite primer feels silky and your barrier cream actually works under makeup.
Beeckman D, Verhaeghe S, Defloor T, et al. A 3-in-1 perineal care washcloth impregnated with dimethicone 3% versus water and pH neutral soap to prevent and treat incontinence-associated dermatitis: a randomized, controlled clinical trial. J Wound Ostomy Continence Nurs. 2011;38(6):627-634.
Saary J, Qureshi R, Palda V, et al. A systematic review of contact dermatitis treatment and prevention. J Am Acad Dermatol. 2005;53(5):845-855. (Barrier creams containing dimethicone prevent irritant contact dermatitis.)
FDA OTC Final Monograph, 21 CFR Part 347 — Skin Protectant Drug Products for Over-the-Counter Human Use; dimethicone listed at section 347.10 as a Category I active ingredient at 1-30%.
Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.
Full ingredient list
Everything on the package label, not just the tracked actives above.
- Contains fragrance: Parfum/Fragrance++, Citronellol, LimoneneWorth knowing if you have sensitive or reactive skin.
- Contains silicones: Cyclohexasiloxane, Dimethicone, Dimethicone/Vinyl Dimethicone CrosspolymerNo irritancy evidence. CIR rates this safe as used; some shoppers avoid it by preference.
+−Show all 58 ingredients
Listed in the order printed on the package. By regulation, ingredients at 1% or higher are listed in descending order by concentration, so the first entry is the largest part of the formula.
- Water/Eau
- Glycerin
- Cyclohexasiloxane
- Hydrogenated Polydecene
- Dipropylene Glycol
- Macadamia Ternifolia Seed Oil
- 1,2-Hexanediol
- Bis-Peg-18 Methyl Ether Dimethyl Silane
- Triethylhexanoin
- Stearyl Alcohol
- Glyceryl Stearate
- Pentaerythrityl Tetraethylhexanoate
- Peg-40 Stearate
- Saccharomyces/Viscum Album (Mistletoe) Ferment Extract
- Lactobacillus/Soybean Ferment Extract
- Saccharomyces/Imperata Cylindrica Root Ferment Extract
- Cetearyl Alcohol
- Cetearyl Olivate
- Sorbitan Olivate
- Hydrogenated Lecithin
- Sorbitan Stearate
- Stearic Acid
- Peg-100 Stearate
- Dimethicone
- Dimethicone/Vinyl Dimethicone Crosspolymer
- Poncirus Trifoliata Fruit Extract
- Panthenol
- Avena Sativa (Oat) Kernel Extract
- Calendula Officinalis Flower Extract
- Nepeta Cataria Extract
- Rubus Idaeus (Raspberry) Leaf Extract
- Baptisia Tinctoria Root Extract
- Stellaria Media (Chickweed) Extract
- Alchemilla Vulgaris Leaf Extract +
- Viola Tricolor Extract +
- Rosa Damascena Flower Extract +
- Spiraea Ulmaria Flower Extract +
- Althaea Officinalis Root Extract +
- Symphytum Officinale Leaf Extract
- Trifolium Pratense (Clover) Flower Extract
- Achillea Millefolium Flower Extract
- Euphrasia Officinalis Extract
- Thuja Occidentalis Leaf Extract
- Menyanthes Trifoliata Leaf Extract
- Salix Alba (Willow) Bark Extract
- Chelidonium Majus Extract
- Urea
- Hydroxyethylpiperazine Ethane Sulfonic Acid
- Glycosyl Trehalose
- Hydrogenated Starch Hydrolysate
- Acrylates/C10-30 Alkyl Acrylate Crosspolymer
- Carbomer
- Xanthan Gum
- Trisodium Edta
- Tromethamine
- Parfum/Fragrance++
- Citronellol
- Limonene
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Not medical advice. GlowPal is educational. Patch-test new products and talk to a qualified healthcare professional before changing your routine, especially if you're pregnant, nursing, or have a diagnosed skin condition. See our terms.