Collagen Cleansing Oil
What it's good for
Key actives from our research database. Click any to read the full evidence dossier.
Signals your skin to make more collagen. Quiet but real support for firmness and fine lines with consistent daily use.
Good for: Anti-aging
A workhorse antioxidant that defends your skin from daily oxidative damage. Pairs especially well with vitamin C, and it's in nearly every good moisturizer for a reason.
Good for: Antioxidant
A signal peptide that tells your skin to make more collagen and elastin. Quiet but consistent firmness support over months of daily use.
Good for: Anti-aging
Sometimes called "topical Botox," it's a peptide that subtly reduces the depth of expression lines around the eyes and forehead when used daily over months. Mild effect, but real.
Good for: Anti-aging
Technically a wax that masquerades as oil, molecularly closer to your own sebum than any other plant oil. Hydrates without clogging pores, calms inflammation, and plays well in acne-prone and sensitive routines.
Good for: Hydrating, Barrier repair, Anti-inflammatory
The protein your skin loses with age, broken down small enough to absorb. Multiple meta-analyses of RCTs show measurable wins in wrinkles, elasticity, and hydration after ~12 weeks. Most evidence is oral, but topical helps surface hydration too.
Good for: Anti-aging, Hydrating
Evidence behind the ingredients
Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.
Signals your skin to make more collagen. Quiet but real support for firmness and fine lines with consistent daily use.
Yang Y et al., Comprehensive evaluation of the efficacy and safety of a new multi-component anti-aging topical eye cream, Skin Research and Technology 2024;30(7):e13790 — 12-week study of active complex containing Matrixyl 3000 peptides showed significant improvement in hydration, elasticity, periorbital wrinkles
Aruan RR et al., Double-blind, Randomized Trial on the Effectiveness of Acetylhexapeptide-3 Cream and Palmitoyl Pentapeptide-4 Cream for Crow's Feet, Journal of Clinical and Aesthetic Dermatology 2023;16(2):37-43 — RCT of topical palmitoyl pentapeptide-4 (Matrixyl) for periorbital wrinkles
Imhof L, Leuthard D, Topical Over-the-Counter Antiaging Agents: An Update and Systematic Review, Dermatology 2021;237(2):217-229 — SR covering topical antiaging peptides
A workhorse antioxidant that defends your skin from daily oxidative damage. Pairs especially well with vitamin C, and it's in nearly every good moisturizer for a reason.
Neves JR et al., Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs, Journal of Cosmetic Dermatology 2022;21(10):4462-4469 — tocopherol-containing antioxidant serum reduced pollution-induced damage and improved aging signs
Warshaw EM et al., Patch Testing With Tocopherol and Tocopherol Acetate: The North American Contact Dermatitis Group Experience, 2001 to 2016, Dermatitis 2021;32(5):308-318 — 15-year NACDG data: positive patch-test reactions to tocopherol rare given widespread cosmetic use
Lin FH et al., Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin, Journal of Investigative Dermatology 2005;125(4):826-832 — ferulic acid + vit C + vit E combo doubled photoprotection vs C+E alone (cross-listed; same paper cited for Ferulic Acid and Vit C)
A signal peptide that tells your skin to make more collagen and elastin. Quiet but consistent firmness support over months of daily use.
Patel MN et al., An Assessment of the Safety, Efficacy, and Tolerability of a Novel Scalp Treatment Regimen Combining a Hydroxy Acid-Based Scrub and Copper Tripeptide Serum in the Management of Seborrheic Dermatitis in Adults, Cureus 2024;16(9):e70108 — 15-day interventional study: copper tripeptide regimen reduced flaking, improved hydration in seborrheic dermatitis
Jiang F et al., Synergy of GHK-Cu and hyaluronic acid on collagen IV upregulation via fibroblast and ex-vivo skin tests, Journal of Cosmetic Dermatology 2023;22(9):2598-2604 — in vitro + ex vivo: GHK-Cu + HA promoted collagen I, IV, and VII; 25.4-fold collagen IV increase in fibroblasts
Dou Y et al., The potential of GHK as an anti-aging peptide, Aging Pathobiology and Therapeutics 2020;2(1):58-61 — narrative review of GHK-Cu's anti-inflammatory and tissue-remodeling mechanisms
+−3 more ingredients
Sometimes called "topical Botox," it's a peptide that subtly reduces the depth of expression lines around the eyes and forehead when used daily over months. Mild effect, but real.
Zhu M et al., The effect of a serum containing acetyl hexapeptide-8, dipeptide diaminobutyroyl benzylamide diacetate and gluconolactone on skin biomarkers, wrinkles and skin texture: ex vivo and clinical studies, International Journal of Cosmetic Science 2026 — two clinical trials (n=50, n=42) showed 35-69% static wrinkle improvement and significant elastic fiber and collagen biomarker increases at 12 weeks
Zdrada-Nowak J, Surgiel-Gemza A, Szatkowska M, Acetyl Hexapeptide-8 in Cosmeceuticals: A Review of Skin Permeability and Efficacy, International Journal of Molecular Sciences 2025
Henseler H, Investigating the effects of Argireline in a skin serum containing hyaluronic acids on skin surface wrinkles using the Visia Complexion Analysis camera system, GMS Interdisciplinary Plastic and Reconstructive Surgery DGPW 2023;12:Doc09 — topical argireline serum reduced measured surface wrinkles
Technically a wax that masquerades as oil, molecularly closer to your own sebum than any other plant oil. Hydrates without clogging pores, calms inflammation, and plays well in acne-prone and sensitive routines.
Tietel Z, Melamed S, Ogen-Shtern N, et al. Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model. Frontiers in Pharmacology. 2024;15:1333085. — Ex-vivo human skin model showing jojoba wax reduced LPS-induced IL-6/IL-8/TNFα by ~30% and enhanced pro-collagen III and hyaluronic acid synthesis.
Blaak J, Staib P, An updated review on efficacy and benefits of sweet almond, evening primrose and jojoba oils in skin care applications, International Journal of Cosmetic Science 2022;44(1):1-9 — jojoba oil documented as effective for strengthening stratum corneum integrity, recovery, and lipid ratio
Lin TK, Zhong L, Santiago JL, Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils, International Journal of Molecular Sciences 2017;19(1):70 — jojoba reviewed among 19 plant oils: supports stratum-corneum lipid replenishment, anti-inflammatory and wound-healing effects
The protein your skin loses with age, broken down small enough to absorb. Multiple meta-analyses of RCTs show measurable wins in wrinkles, elasticity, and hydration after ~12 weeks. Most evidence is oral, but topical helps surface hydration too.
Reilly DM, Kynaston L, Naseem S, Proudman E, Laceby D. A Clinical Trial Shows Improvement in Skin Collagen, Hydration, Elasticity, Wrinkles, Scalp, and Hair Condition following 12-Week Oral Intake of a Supplement Containing Hydrolysed Collagen. Dermatology Research and Practice. 2024. — Randomized double-blind placebo-controlled trial; 12-week oral collagen supplement showed 44.6% decrease in collagen fragmentation, +13.8% hydration, +22.7% elasticity, -19.6% wrinkle index vs placebo.
Demir-Dora D, Ozsoy U, Yildirim Y, et al. The Efficacy and Safety of CollaSel Pro® Hydrolyzed Collagen Peptide Supplementation without Addons in Improving Skin Health in Adult Females: A Double Blind, Randomized, Placebo-Controlled Clinical Study. Journal of Clinical Medicine. 2024 Sep 11. — Double-blind RCT (n=112); significant improvements in skin elasticity (p=0.009), hydration (p<0.001), and roughness vs placebo.
Pu SY et al., Effects of Oral Collagen for Skin Anti-Aging: A Systematic Review and Meta-Analysis, Nutrients 2023;15(9):2080 — 26 RCTs / 1,721 patients: hydrolyzed collagen significantly improved skin hydration and elasticity vs placebo across multiple collagen sources
Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.
Full ingredient list
Everything on the package label, not just the tracked actives above.
+−Show all 34 ingredients
Listed in the order printed on the package. By regulation, ingredients at 1% or higher are listed in descending order by concentration, so the first entry is the largest part of the formula.
- Ethylhexyl Palmitate
- Cetyl Ethylhexanoate
- Polyglyceryl-10 Diisostearate
- Polyglyceryl-6 Dicaprate
- Sorbitan Sesquioleate
- Polyglyceryl-2 Laurate
- Water
- Pyrus Communis (Pear) Fruit Extract
- Rosa Damascena Flower Water
- Eclipta Prostrata Extract
- Iris Florentina Root Extract
- Cucumis Melo (Melon) Seed Extract
- Hedera Helix (Ivy) Leaf/Stem Extract
- Melia Azadirachta Leaf Extract
- Caprylyl Glycol
- Vitis Vinifera (Grape) Seed Oil
- Helianthus Annuus (Sunflower) Seed Oil
- Simmondsia Chinensis (Jojoba) Seed Oil
- Ethylhexylglycerin
- Moringa Oleifera Seed Oil
- Butylene Glycol
- 1,2-Hexanediol
- Collagen Extract
- Acetyl Hexapeptide-8
- Tocopherol
- Oligopeptide-1
- Copper Tripeptide-1
- Palmitoyl Pentapeptide-4
- Palmitoyl Tripeptide-5
- Tripeptide-1
- Hexapeptide-9
- Palmitoyl Tripeptide-38
- Pentapeptide-4
- Hexapeptide-12
Similar comparisons
Not medical advice. GlowPal is educational. Patch-test new products and talk to a qualified healthcare professional before changing your routine, especially if you're pregnant, nursing, or have a diagnosed skin condition. See our terms.