Dramatically Different Moisturizing Lotion+
What it's good for
Key actives from our research database. Click any to read the full evidence dossier.
A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.
Good for: Hydrating
A small molecule your skin already makes. Low concentrations deeply hydrate dry skin; higher concentrations soften thick, scaly patches. A workhorse for very dry, rough, or flaky skin.
Good for: Hydrating, Barrier repair, Exfoliating
A pure hydrator that holds water in your skin. Makes skin look plumper and smoother almost immediately.
Good for: Hydrating
Evidence behind the ingredients
Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.
A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.
Danby SG et al., Different types of emollient cream exhibit diverse physiological effects on the skin barrier in adults with atopic dermatitis, Clinical and Experimental Dermatology 2022;47(6):1154-1164 — glycerol+urea emollient delivered superior barrier-strengthening and irritant protection
Youssef R et al., Glycerol 85% efficacy on atopic skin and its microbiome: a randomized controlled trial, Journal of Dermatological Treatment 2021;32(7):730-736 — topical glycerol 85% RCT on atopic skin
Evans NJ et al., Human axillary skin condition is improved following incorporation of glycerol into the stratum corneum from an antiperspirant formulation, Archives of Dermatological Research 2017;309(9):739-748 — 4% glycerol penetrated axillary SC, reduced irritation, improved hydration
A small molecule your skin already makes. Low concentrations deeply hydrate dry skin; higher concentrations soften thick, scaly patches. A workhorse for very dry, rough, or flaky skin.
Jawed I et al., Effect of topical treatment with urea in ichthyosis, atopic dermatitis, psoriasis, and other skin conditions: a systematic review, Annals of Medicine and Surgery 2025
Treesirichod A et al., The efficacy and safety of 20% urea cream and 10% urea cream in the treatment of acanthosis nigricans in adolescents: a randomized comparative double-blind study, Journal of Cosmetic Dermatology 2022;21(7):2859-2864 — topical urea cream improved acanthosis nigricans
Piquero-Casals J, Morgado-Carrasco D, Granger C, Trullas C, Jesus-Silva A, Krutmann J, Urea in Dermatology: A Review of its Emollient, Moisturizing, Keratolytic, Skin Barrier Enhancing and Antimicrobial Properties, Dermatology and Therapy (Heidelberg) 2021;11(6):1905-1915
A pure hydrator that holds water in your skin. Makes skin look plumper and smoother almost immediately.
Karabat MU, Tuncer MC. Effects of hyaluronic acid on skin at the cellular level: a systematic review. Rev Assoc Med Bras. 2025;71(8):e20250208. — Systematic review of 45 studies found low-molecular-weight HA stimulates keratinocyte proliferation and migration while high-molecular-weight HA drives skin hydration, supporting topical HA as an effective skin-hydrating and barrier-supporting ingredient.
Bravo B et al., Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence, Dermatology and Therapy 2022;12(12):2657-2680 — HA-based cosmeceuticals reliably improve hydration and signs of skin aging
Lee SG et al., Hyaluronan Oligosaccharides Improve Rosacea-Like Phenotype through Anti-Inflammatory and Epidermal Barrier-Improving Effects, Annals of Dermatology 2020
Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.
Full ingredient list
Everything on the package label, not just the tracked actives above.
+−Show all 22 ingredients
Listed in the order printed on the package. By regulation, ingredients at 1% or higher are listed in descending order by concentration, so the first entry is the largest part of the formula.
- Water
- Mineral Oil/Paraffinum Liquidum/Huile Minerale
- Glycerin
- Petrolatum
- Stearic Acid
- Glyceryl Stearate
- Sesamum Indicum (Sesame) Oil
- Urea
- Lanolin Alcohol
- Triethanolamine
- Hordeum Vulgare (Barley) Extract/Extrait D'Orge
- Cucumis Sativus (Cucumber) Fruit Extract
- Helianthus Annuus (Sunflower) Seedcake
- Propylene Glycol Dicaprate
- Sodium Hyaluronate
- Butylene Glycol
- Pentylene Glycol
- Trisodium Edta
- Phenoxyethanol
- Yellow 6 (Ci 15985)
- Yellow 5 (Ci 19140)
- Red 33 (Ci 17200)
Similar comparisons
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