Differin Adapalene Gel 0.1% vs La Roche-Posay Retinol B3 Serum
Differin
Adapalene Gel 0.1%
~$16· 15 g
Adapalene
La Roche-Posay
Retinol B3 Serum
~$45· 1 fl oz
RetinolNiacinamideHyaluronic Acid+1 more
Actives breakdown
| Active ingredient | Differin | La Roche-Posay |
|---|---|---|
| Adapalene | ✓ | — |
| Retinol | — | ✓ |
| Niacinamide | — | ✓ |
| Hyaluronic Acid | — | ✓ |
| Glycerin | — | ✓ |
Layering & Safety
Combined Verdict
Safe to layer
No layering conflicts flagged between these two. Patch-test new actives as usual.