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Shop TIRTIR Ceramic Milk Ampoule
Serum
TIRTIR

Ceramic Milk Ampoule

~$25· 40ml / 1.35 fl oz
DrynessFine lines & firmnessUneven texture

What it's good for

Key actives from our research database. Click any to read the full evidence dossier.

  • CeramidesStrong evidenceFull dossier ↗

    Refills the natural barrier between your skin cells. Locks moisture in, keeps irritants out, calms dry or damaged skin.

    Good for: Barrier repair

  • Rice Bran ExtractModerate evidenceFull dossier ↗

    A traditional Japanese brightener with built-in antioxidants. Softens, hydrates, and adds glow.

    Good for: Brightening, Antioxidant

  • Matrixyl PeptidesModerate evidenceFull dossier ↗

    Signals your skin to make more collagen. Quiet but real support for firmness and fine lines with consistent daily use.

    Good for: Anti-aging

  • GlycerinModerate evidenceFull dossier ↗

    A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.

    Good for: Hydrating

Evidence behind the ingredients

Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.

CeramidesStrong evidence7 citations

Refills the natural barrier between your skin cells. Locks moisture in, keeps irritants out, calms dry or damaged skin.

Andrew PV et al., Topical supplementation with physiological lipids rebalances the stratum corneum ceramide profile and strengthens skin barrier function in adults predisposed to atopic dermatitis, British Journal of Dermatology 2025;193(4):729-740 — physiological-lipid emulsion raised SC ceramide NP/AP and improved barrier function vs control

2025Positive (efficacy)PMID:40408261View source ↗

Nugroho WT, Sawitri, Astindari, Utomo B, Listiawan MY, Ervianti E, Astari L. The Efficacy of Moisturisers Containing Ceramide Compared with Other Moisturisers in the Management of Atopic Dermatitis: A Systematic Literature Review and Meta-Analysis. Indian J Dermatol. 2023;68(1):53-58. — Meta-analysis of 5 studies found ceramide-containing moisturisers produced significantly greater improvement in SCORAD compared with non-ceramide moisturisers in atopic dermatitis.

2023Meta-analysis (positive)PMID:37151263View source ↗

Shindo S et al., Effects of a moisturizer containing pseudo-ceramide and a eucalyptus extract on sweating function in adult atopic dermatitis: a double-blind, randomized, controlled left-right comparison clinical trial, Journal of Cosmetic Dermatology 2022;21(10):4503-4509 — pseudo-ceramide + eucalyptus moisturizer restored sweating function and barrier in AD adults

2022Positive (efficacy)PMID:35298858View source ↗
Rice Bran ExtractModerate evidence5 citations

A traditional Japanese brightener with built-in antioxidants. Softens, hydrates, and adds glow.

Zhou J et al., Exploratory study on the effect of ferulic acid derived from rice bran on dull skin, Drug Discoveries & Therapeutics 2026 (online ahead of print) — topical rice-bran ferulic acid improved facial dullness/melanin index

2026Positive (efficacy)PMID:42324157View source ↗

Zamil DH et al., Dermatological uses of rice products: Trend or true?, Journal of Cosmetic Dermatology 2022;21(11):6056-6060 — review of rice-derived ingredients with antiaging, anti-inflammatory, brightening, photoprotective effects

2022Mechanism onlyPMID:35587098View source ↗

Miyasaka K et al., Anti-melanogenic effects of glucosylceramides and elasticamide derived from rice oil by-products in melanoma cells, melanocytes, and human skin, Journal of Food Biochemistry 2022;46(10):e14353 — rice-derived ceramides/elasticamide suppressed UV-induced pigmentation

2022Positive (efficacy)PMID:35986572View source ↗
Matrixyl PeptidesModerate evidence6 citations

Signals your skin to make more collagen. Quiet but real support for firmness and fine lines with consistent daily use.

Yang Y et al., Comprehensive evaluation of the efficacy and safety of a new multi-component anti-aging topical eye cream, Skin Research and Technology 2024;30(7):e13790 — 12-week study of active complex containing Matrixyl 3000 peptides showed significant improvement in hydration, elasticity, periorbital wrinkles

2024Positive (efficacy)PMID:38932444View source ↗

Aruan RR et al., Double-blind, Randomized Trial on the Effectiveness of Acetylhexapeptide-3 Cream and Palmitoyl Pentapeptide-4 Cream for Crow's Feet, Journal of Clinical and Aesthetic Dermatology 2023;16(2):37-43 — RCT of topical palmitoyl pentapeptide-4 (Matrixyl) for periorbital wrinkles

2023Positive (efficacy)PMID:36909866View source ↗

Imhof L, Leuthard D, Topical Over-the-Counter Antiaging Agents: An Update and Systematic Review, Dermatology 2021;237(2):217-229 — SR covering topical antiaging peptides

2021Meta-analysis (positive)PMID:32882685View source ↗
+1 more ingredient
GlycerinModerate evidence6 citations

A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.

Danby SG et al., Different types of emollient cream exhibit diverse physiological effects on the skin barrier in adults with atopic dermatitis, Clinical and Experimental Dermatology 2022;47(6):1154-1164 — glycerol+urea emollient delivered superior barrier-strengthening and irritant protection

2022Positive (efficacy)PMID:35167133View source ↗

Youssef R et al., Glycerol 85% efficacy on atopic skin and its microbiome: a randomized controlled trial, Journal of Dermatological Treatment 2021;32(7):730-736 — topical glycerol 85% RCT on atopic skin

2021Positive (efficacy)PMID:31869257View source ↗

Evans NJ et al., Human axillary skin condition is improved following incorporation of glycerol into the stratum corneum from an antiperspirant formulation, Archives of Dermatological Research 2017;309(9):739-748 — 4% glycerol penetrated axillary SC, reduced irritation, improved hydration

2017Positive (efficacy)PMID:28889318View source ↗

Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.

Similar comparisons

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