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Shop Tocobo CICA Calming Aqua Toner
Toner
Tocobo

CICA Calming Aqua Toner

~$20· 200 ml / 6.76 fl oz
RednessDrynessUneven texture

What it's good for

Key actives from our research database. Click any to read the full evidence dossier.

  • Centella AsiaticaModerate evidenceFull dossier ↗

    Also called "cica," it calms redness, repairs the skin barrier, and speeds up recovery. The go-to for irritated or reactive skin.

    Good for: Anti-inflammatory, Barrier repair

  • Hyaluronic AcidStrong evidenceFull dossier ↗

    A pure hydrator that holds water in your skin. Makes skin look plumper and smoother almost immediately.

    Good for: Hydrating

  • Bifida Ferment LysateModerate evidenceFull dossier ↗

    A probiotic-based ingredient that strengthens your skin's defenses against irritation and environmental stress.

    Good for: Barrier repair, Anti-inflammatory

  • NiacinamideStrong evidenceFull dossier ↗

    A multitasker that calms redness, evens out skin tone, and helps oily skin balance out. One of the safest do-a-little-of-everything ingredients.

    Good for: Brightening, Barrier repair, Anti-inflammatory

  • PanthenolModerate evidenceFull dossier ↗

    Pro-vitamin B5. Deeply hydrates and helps repair the skin barrier, calming dry or compromised skin.

    Good for: Hydrating, Barrier repair

  • AllantoinAnecdotal evidenceFull dossier ↗

    A gentle smoother and skin-soother. Reduces flakiness and helps the surface look more even.

    Good for: Anti-inflammatory, Hydrating

  • MadecassosideModerate evidenceFull dossier ↗

    A purified compound from the cica (centella) plant, laser-focused on calming inflammation and speeding up how fast skin recovers.

    Good for: Anti-inflammatory, Barrier repair

Evidence behind the ingredients

Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.

Centella AsiaticaModerate evidence6 citations

Also called "cica," it calms redness, repairs the skin barrier, and speeds up recovery. The go-to for irritated or reactive skin.

Hur N et al., A Randomized, Double-Blind, Placebo-Controlled Trial Assessing the Effects of Oral Centella asiatica Extract on Skin Aging-Related Parameters in Middle-Aged Korean Women, Nutrients 2026

2026Positive (efficacy)PMID:42196964View source ↗

Borowicz KK et al., Geroprotective Potential of Centella asiatica: Modulation of Cellular Aging, Nutrients 2026

2026Mechanism onlyPMID:42280293View source ↗

Witkowska K et al., Topical Application of Centella asiatica in Wound Healing: Recent Insights into Mechanisms and Clinical Efficacy, Pharmaceutics 2024;16(10):1252 — modern hydrogel and nanostructured Centella delivery systems accelerate wound healing across wound types

2024Meta-analysis (positive)PMID:39458583View source ↗
Hyaluronic AcidStrong evidence7 citations

A pure hydrator that holds water in your skin. Makes skin look plumper and smoother almost immediately.

Karabat MU, Tuncer MC. Effects of hyaluronic acid on skin at the cellular level: a systematic review. Rev Assoc Med Bras. 2025;71(8):e20250208. — Systematic review of 45 studies found low-molecular-weight HA stimulates keratinocyte proliferation and migration while high-molecular-weight HA drives skin hydration, supporting topical HA as an effective skin-hydrating and barrier-supporting ingredient.

2025Meta-analysis (positive)PMID:40990743View source ↗

Bravo B et al., Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence, Dermatology and Therapy 2022;12(12):2657-2680 — HA-based cosmeceuticals reliably improve hydration and signs of skin aging

2022Meta-analysis (positive)PMID:36200921View source ↗

Lee SG et al., Hyaluronan Oligosaccharides Improve Rosacea-Like Phenotype through Anti-Inflammatory and Epidermal Barrier-Improving Effects, Annals of Dermatology 2020

2020Mechanism onlyPMID:33911737View source ↗
Bifida Ferment LysateModerate evidence6 citations

A probiotic-based ingredient that strengthens your skin's defenses against irritation and environmental stress.

Zhu X et al., Protective effect of Bifidobacterium animalis CGMCC25262 on HaCaT keratinocytes, International Microbiology 2024;27(5):1417-1428 — B. animalis lysate upregulated HAS-2, AQP3, FLG and reduced RANTES under TNF-α/IFN-γ

2024Mechanism onlyPMID:38278974View source ↗

Wang Y et al., Short-term skin reactions and changes in stratum corneum following different ways of facial sheet mask usage, Journal of Tissue Viability 2024;33(4):831-839 — evaluated topical bifida ferment lysate masks on skin barrier measures

2024Positive (efficacy)PMID:38951050View source ↗

Wang R et al., The pivotal role of Bifida Ferment Lysate on reinforcing the skin barrier function and maintaining homeostasis of skin defenses in vitro, Journal of Cosmetic Dermatology 2023;22(12):3427-3435 — BFL upregulated barrier and antioxidant genes; reduced inflammatory signaling

2023Mechanism onlyPMID:37218728View source ↗
+4 more ingredients
NiacinamideStrong evidence10 citations

A multitasker that calms redness, evens out skin tone, and helps oily skin balance out. One of the safest do-a-little-of-everything ingredients.

Moro F et al., Skin Cancer Prevention and Antiaging: Role of Nicotinamide, International Journal of Molecular Sciences 2026

2026Mechanism onlyPMID:42278444View source ↗

Passeron T et al., An Investigator-Blinded, Randomized Trial of a Broad-Spectrum Sunscreen Containing Sclareolide and Niacinamide, Dermatology and Therapy (Heidelberg) 2026

2026Positive (efficacy)PMID:41240206View source ↗

Vergilio MM et al., Topical Formulation with Niacinamide Combined with 5 MHz Ultrasound for Improving Skin Ageing, Current Medicinal Chemistry 2025

2025Positive (efficacy)PMID:39171587View source ↗
PanthenolModerate evidence5 citations

Pro-vitamin B5. Deeply hydrates and helps repair the skin barrier, calming dry or compromised skin.

Gao Y et al., Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment, Journal of Cosmetic Dermatology 2025;24(7):e70223 — double-blind RCT (n=60): panthenol mask decreased erythema, enhanced hydration, repaired barrier vs saline

2025Positive (efficacy)PMID:40613435View source ↗

Cho YS et al., Use of Dexpanthenol for Atopic Dermatitis-Benefits and Recommendations Based on Current Evidence, Journal of Clinical Medicine 2022;11(14):3943 — Korean-authored review; dexpanthenol improves barrier and reduces severity in mild-to-moderate AD

2022Meta-analysis (positive)PMID:35887707View source ↗

Heise R et al., Accelerated wound healing with a dexpanthenol-containing ointment after fractional ablative CO2 laser resurfacing of photo-damaged skin in a randomized prospective clinical trial, Cutaneous and Ocular Toxicology 2019;38(3):274-278 — RCT: dexpanthenol significantly faster wound closure vs petroleum jelly post-laser

2019Positive (efficacy)PMID:30897983View source ↗
AllantoinAnecdotal evidence6 citations

A gentle smoother and skin-soother. Reduces flakiness and helps the surface look more even.

Xu Z et al., Efficacy and Safety of Topical Compound Heparin Sodium Allantoin Gel for the Treatment of Rosacea, Journal of Cosmetic Dermatology 2025;24(4):e70129 — RCT (n=82, 12 weeks): allantoin gel improved erythema and alleviated itching/burning vs traditional therapy

2025Positive (efficacy)PMID:40177799View source ↗

Tan C et al., The combination of allantoin, bisabolol, D-panthenol and dipotassium glycyrrhizinate mitigates UVB-induced PGE2 synthesis by keratinocytes, International Journal of Cosmetic Science 2024;46(5):691-701 — in vitro: allantoin combination reduced UVB-induced PGE2, IL-1α, IL-6, IL-8, TNFα

2024Mechanism onlyPMID:38433250View source ↗

Saucedo-Acuna RA et al. (Mexico), Characterization and In Vivo Assay of Allantoin-Enriched Pectin Hydrogel for the Treatment of Skin Wounds, International Journal of Molecular Sciences 2023;24(8):7377 — allantoin-pectin hydrogel reduced wound healing time by ~71% with complete closure at day 15 in rat model

2023Mechanism onlyPMID:37108540View source ↗
MadecassosideModerate evidence6 citations

A purified compound from the cica (centella) plant, laser-focused on calming inflammation and speeding up how fast skin recovers.

Liu L et al., Madecassoside Attenuated UVB Irradiation-Induced Skin Ferroptosis by Targeting POR, Phytomedicine 2026

2026Mechanism onlyPMID:41421280View source ↗

Bandopadhyay S et al., Therapeutic properties and pharmacological activities of asiaticoside and madecassoside: A review, Journal of Cellular and Molecular Medicine 2023;27(5):593-608 — comprehensive review of wound-healing, anti-inflammatory and regenerative activity

2023Meta-analysis (positive)PMID:36756687View source ↗

Park KS, Pharmacological Effects of Centella asiatica on Skin Diseases: Evidence and Possible Mechanisms, Evidence-Based Complementary and Alternative Medicine 2021;2021:5462633 — KR-authored review of triterpenes including madecassoside

2021Meta-analysis (positive)PMID:34845411View source ↗

Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.

Full ingredient list

Everything on the package label, not just the tracked actives above.

Drying alcohol freeSulfates freeParabens freeSilicones free
  • Contains fragrance: FragranceWorth knowing if you have sensitive or reactive skin.
+Show all 52 ingredients

Listed in the order printed on the package. By regulation, ingredients at 1% or higher are listed in descending order by concentration, so the first entry is the largest part of the formula.

  1. Water
  2. Butylene Glycol
  3. Dipropylene Glycol
  4. Glycerin
  5. Xylitol
  6. 1,2-Hexanediol
  7. Erythritol
  8. Polyglyceryl-10 Laurate
  9. Camellia Sinensis Leaf Water
  10. Carbomer
  11. Tromethamine
  12. Allantoin
  13. Xanthan Gum
  14. Gluconolactone
  15. Mentha Aquatica Leaf Extract
  16. Aloe Ferox Leaf Extract
  17. Melia Azadirachta Leaf Extract
  18. Salvia Sclarea (Clary) Extract
  19. Borago Officinalis Extract
  20. Chamomilla Recutita (Matricaria) Flower Extract
  21. Centaurea Cyanus Flower Extract
  22. Lavandula Angustifolia (Lavender) Flower Extract
  23. Hyacinthus Orientalis (Hyacinth) Extract
  24. Melia Azadirachta Flower Extract
  25. Lactococcus Ferment Lysate
  26. Lactobacillus Ferment Lysate
  27. Centella Asiatica Leaf Extract
  28. Bifida Ferment Lysate
  29. Niacinamide
  30. Carica Papaya (Papaya) Fruit Extract
  31. Malus Domestica Fruit Extract
  32. Prunus Mume Fruit Extract
  33. Vitis Vinifera (Grape) Fruit Extract
  34. Sodium Hyaluronate
  35. Panthenol
  36. Hydrogenated Lecithin
  37. Asiaticoside
  38. Asiatic Acid
  39. Madecassic Acid
  40. Tocopherol
  41. Hydroxypropyltrimonium Hyaluronate
  42. Hydrolyzed Hyaluronic Acid
  43. Beta-Glucan
  44. Ceramide NP
  45. Sodium Acetylated Hyaluronate
  46. Hyaluronic Acid
  47. Hydrolyzed Sodium Hyaluronate
  48. Sodium Hyaluronate Crosspolymer
  49. Potassium Hyaluronate
  50. Ethylhexylglycerin
  51. Disodium EDTA
  52. Fragrance

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