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Shop Bio essence Bio-gold 24k Gold Radiance Cleanser
Cleanser
Bio essence

Bio-gold 24k Gold Radiance Cleanser

~$17· 1 Count (Pack of 1)

What it's good for

Key actives from our research database. Click any to read the full evidence dossier.

  • Aloe VeraModerate evidenceFull dossier ↗

    Calms irritation and adds light hydration. The classic for sunburned or reactive skin.

    Good for: Anti-inflammatory, Hydrating

  • Alpha ArbutinModerate evidenceFull dossier ↗

    A safer, slower-acting alternative to prescription-strength dark-spot faders. Built for long-term use without irritation.

    Good for: Brightening

  • EGCG (Green Tea)Strong evidenceFull dossier ↗

    A polyphenol from green tea that calms UV-triggered redness and reinforces your sunscreen as a second line of antioxidant defense.

    Good for: Antioxidant, Anti-inflammatory, Sun protection

  • GlycerinModerate evidenceFull dossier ↗

    A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.

    Good for: Hydrating

  • Hyaluronic AcidStrong evidenceFull dossier ↗

    A pure hydrator that holds water in your skin. Makes skin look plumper and smoother almost immediately.

    Good for: Hydrating

  • Lauric AcidAnecdotal evidenceFull dossier ↗

    A fatty acid from coconut oil with striking antimicrobial activity against acne bacteria. In lab tests it outperforms benzoyl peroxide at lower concentrations. The research is promising but limited to in vitro and animal models; no large human RCT yet. Worth noting: the concentrations used in the studies are far higher than what arrives via a coconut-oil facial oil, so look for formulas that list it as a dedicated active if you want the therapeutic dose.

    Good for: Anti-acne, Anti-inflammatory

  • NiacinamideStrong evidenceFull dossier ↗

    A multitasker that calms redness, evens out skin tone, and helps oily skin balance out. One of the safest do-a-little-of-everything ingredients.

    Good for: Brightening, Barrier repair, Anti-inflammatory

  • Vitamin EModerate evidenceFull dossier ↗

    A workhorse antioxidant that defends your skin from daily oxidative damage. Pairs especially well with vitamin C, and it's in nearly every good moisturizer for a reason.

    Good for: Antioxidant

Evidence behind the ingredients

Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.

Aloe VeraModerate evidence7 citations

Calms irritation and adds light hydration. The classic for sunburned or reactive skin.

Huang YN et al., Effects of Aloe vera on Burn Injuries: A Systematic Review and Meta-Analysis of Randomized Controlled Trials, Journal of Burn Care & Research 2024;45(6):1536-1545 — topical aloe vera reduced burn wound-healing time

2024Meta-analysis (positive)PMID:38605441View source ↗

Tungkasamit T et al., Reduction in severity of radiation-induced dermatitis in head and neck cancer patients treated with topical aloe vera gel: A randomized multicenter double-blind placebo-controlled trial, European Journal of Oncology Nursing 2022;59:102164 — aloe vera reduced severity of moderate-to-severe radiation dermatitis

2022Positive (efficacy)PMID:35767935View source ↗

Sharma S et al., Second-Degree Burns and Aloe Vera: A Meta-analysis and Systematic Review, Advances in Skin & Wound Care 2022;35(11):1-9 — topical aloe vera shortened time to healing for second-degree burns

2022Meta-analysis (positive)PMID:36264753View source ↗
Alpha ArbutinModerate evidence5 citations

A safer, slower-acting alternative to prescription-strength dark-spot faders. Built for long-term use without irritation.

Ma ZY, Lu Y, Melanin synthesis and regulation in vivo and commonly used melanin inhibitors from natural products and traditional Chinese medicine, Zhongguo Zhong Yao Za Zhi (China Journal of Chinese Materia Medica) 2020;45(24):5898-5916 — Beijing University of Chinese Medicine review classifies arbutin among tyrosinase-active-site-targeting melanin inhibitors

2020Mechanism onlyPMID:33496130View source ↗

Morag M et al., A double-blind, placebo-controlled randomized trial of Serratulae quinquefoliae folium, a new source of β-arbutin, in selected skin hyperpigmentations, Journal of Cosmetic Dermatology 2015 — 76% of melasma patients showed clinical lightening over 8 weeks

2015Positive (efficacy)PMID:26119285View source ↗

Kim H, Choi HR, Kim DS, Park KC, Topical hypopigmenting agents for pigmentary disorders and their mechanisms of action, Annals of Dermatology 2012;24(1):1-6 — review classifies arbutin among hypopigmenting agents via tyrosinase regulation as a hydroquinone alternative

2012Mechanism onlyPMID:22363147View source ↗
EGCG (Green Tea)Strong evidence7 citations

A polyphenol from green tea that calms UV-triggered redness and reinforces your sunscreen as a second line of antioxidant defense.

Detudom P, Kamanamool N, Paichitrojjana A, Udompataikul P, Udompataikul M, Efficacy of anti-sebum moisturizing cream containing 2% l-carnitine and 5% epigallocatechin gallate in seborrhea, Journal of Cosmetic Dermatology 2023;22(11):3058-3064 — Thai RCT showed EGCG-containing cream significantly reduced sebum and improved hydration in seborrhea

2023Positive (efficacy)PMID:37194909View source ↗

Ud-Din S et al., A Double-Blind, Randomized Trial Shows the Role of Zonal Priming and Direct Topical Application of Epigallocatechin-3-Gallate in the Modulation of Cutaneous Scarring in Human Skin, Journal of Investigative Dermatology 2019;139(8):1680-1690 — topical EGCG reduced scar thickness weeks 1-3 and increased elasticity at week 4 vs placebo

2019Positive (efficacy)PMID:30822414View source ↗

Kim YR et al., Clinical Evaluation of a New-Formula Shampoo for Scalp Seborrheic Dermatitis Containing Rosa centifolia + EGCG: A Randomized Double-Blind Controlled Study, Annals of Dermatology 2014;26(6):733-8 — EGCG-containing shampoo matched ketoconazole and zinc pyrithione efficacy; faster erythema response than 1% zinc pyrithione

2014Positive (efficacy)PMID:25473226View source ↗
+5 more ingredients
GlycerinModerate evidence6 citations

A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.

Danby SG et al., Different types of emollient cream exhibit diverse physiological effects on the skin barrier in adults with atopic dermatitis, Clinical and Experimental Dermatology 2022;47(6):1154-1164 — glycerol+urea emollient delivered superior barrier-strengthening and irritant protection

2022Positive (efficacy)PMID:35167133View source ↗

Youssef R et al., Glycerol 85% efficacy on atopic skin and its microbiome: a randomized controlled trial, Journal of Dermatological Treatment 2021;32(7):730-736 — topical glycerol 85% RCT on atopic skin

2021Positive (efficacy)PMID:31869257View source ↗

Evans NJ et al., Human axillary skin condition is improved following incorporation of glycerol into the stratum corneum from an antiperspirant formulation, Archives of Dermatological Research 2017;309(9):739-748 — 4% glycerol penetrated axillary SC, reduced irritation, improved hydration

2017Positive (efficacy)PMID:28889318View source ↗
Hyaluronic AcidStrong evidence7 citations

A pure hydrator that holds water in your skin. Makes skin look plumper and smoother almost immediately.

Karabat MU, Tuncer MC. Effects of hyaluronic acid on skin at the cellular level: a systematic review. Rev Assoc Med Bras. 2025;71(8):e20250208. — Systematic review of 45 studies found low-molecular-weight HA stimulates keratinocyte proliferation and migration while high-molecular-weight HA drives skin hydration, supporting topical HA as an effective skin-hydrating and barrier-supporting ingredient.

2025Meta-analysis (positive)PMID:40990743View source ↗

Bravo B et al., Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence, Dermatology and Therapy 2022;12(12):2657-2680 — HA-based cosmeceuticals reliably improve hydration and signs of skin aging

2022Meta-analysis (positive)PMID:36200921View source ↗

Lee SG et al., Hyaluronan Oligosaccharides Improve Rosacea-Like Phenotype through Anti-Inflammatory and Epidermal Barrier-Improving Effects, Annals of Dermatology 2020

2020Mechanism onlyPMID:33911737View source ↗
Lauric AcidAnecdotal evidence2 citations

A fatty acid from coconut oil with striking antimicrobial activity against acne bacteria. In lab tests it outperforms benzoyl peroxide at lower concentrations. The research is promising but limited to in vitro and animal models; no large human RCT yet. Worth noting: the concentrations used in the studies are far higher than what arrives via a coconut-oil facial oil, so look for formulas that list it as a dedicated active if you want the therapeutic dose.

Nakatsuji T, Kao MC, Fang JY, Zouboulis CC, Zhang L, Gallo RL, Huang CM. Antimicrobial property of lauric acid against Propionibacterium acnes: its therapeutic potential for inflammatory acne vulgaris. J Invest Dermatol. 2009;129(10):2480-2488.

2009Positive (efficacy)PMID:19387482View source ↗

Yang D, Pornpattananangkul D, Nakatsuji T, Chan M, Carson D, Huang CM, Zhang L. The antimicrobial activity of liposomal lauric acids against Propionibacterium acnes. Biomaterials. 2009;30(30):6035-6040.

2009Positive (efficacy)PMID:19665786View source ↗
NiacinamideStrong evidence10 citations

A multitasker that calms redness, evens out skin tone, and helps oily skin balance out. One of the safest do-a-little-of-everything ingredients.

Moro F et al., Skin Cancer Prevention and Antiaging: Role of Nicotinamide, International Journal of Molecular Sciences 2026

2026Mechanism onlyPMID:42278444View source ↗

Passeron T et al., An Investigator-Blinded, Randomized Trial of a Broad-Spectrum Sunscreen Containing Sclareolide and Niacinamide, Dermatology and Therapy (Heidelberg) 2026

2026Positive (efficacy)PMID:41240206View source ↗

Vergilio MM et al., Topical Formulation with Niacinamide Combined with 5 MHz Ultrasound for Improving Skin Ageing, Current Medicinal Chemistry 2025

2025Positive (efficacy)PMID:39171587View source ↗
Vitamin EModerate evidence6 citations

A workhorse antioxidant that defends your skin from daily oxidative damage. Pairs especially well with vitamin C, and it's in nearly every good moisturizer for a reason.

Neves JR et al., Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs, Journal of Cosmetic Dermatology 2022;21(10):4462-4469 — tocopherol-containing antioxidant serum reduced pollution-induced damage and improved aging signs

2022Positive (efficacy)PMID:35150043View source ↗

Warshaw EM et al., Patch Testing With Tocopherol and Tocopherol Acetate: The North American Contact Dermatitis Group Experience, 2001 to 2016, Dermatitis 2021;32(5):308-318 — 15-year NACDG data: positive patch-test reactions to tocopherol rare given widespread cosmetic use

2021Safety assessmentPMID:34238818View source ↗

Lin FH et al., Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin, Journal of Investigative Dermatology 2005;125(4):826-832 — ferulic acid + vit C + vit E combo doubled photoprotection vs C+E alone (cross-listed; same paper cited for Ferulic Acid and Vit C)

2005Positive (efficacy)PMID:16185284View source ↗

Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.

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