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Salmon Oil Nutrition Eye Cream

~$20· 1.18 Fl Oz

What it's good for

Key actives from our research database. Click any to read the full evidence dossier.

  • AdenosineModerate evidenceFull dossier ↗

    A Korean-approved anti-wrinkle ingredient that encourages collagen production for a smoother, firmer look.

    Good for: Anti-aging

  • Argan OilModerate evidenceFull dossier ↗

    The Moroccan kitchen-staple oil with real cosmetic data behind it. Daily use measurably improves skin elasticity in postmenopausal women. Good for dry, mature, or barrier-compromised skin without feeling greasy.

    Good for: Hydrating, Barrier repair, Antioxidant

  • ArgirelineModerate evidenceFull dossier ↗

    Sometimes called "topical Botox," it's a peptide that subtly reduces the depth of expression lines around the eyes and forehead when used daily over months. Mild effect, but real.

    Good for: Anti-aging

  • BeeswaxModerate evidenceFull dossier ↗

    A wax film former that quietly does what petrolatum does (slows water loss and shields chapped skin) without feeling slick. Most evidence comes from honey/beeswax/olive-oil cerates that have shown improvement in dry, irritation-prone skin in controlled trials. CIR-affirmed safe.

    Good for: Barrier repair, Hydrating

  • Copper PeptidesModerate evidenceFull dossier ↗

    A signal peptide that tells your skin to make more collagen and elastin. Quiet but consistent firmness support over months of daily use.

    Good for: Anti-aging

  • DimethiconeStrong evidenceFull dossier ↗

    A silicone that sits on your skin as an invisible, non-greasy shield. Reduces water loss, protects against irritants (think soap, friction, incontinence), and is FDA-recognised as a skin protectant from 1-30%. The reason your favourite primer feels silky and your barrier cream actually works under makeup.

    Good for: Barrier repair, Hydrating

  • GlycerinModerate evidenceFull dossier ↗

    A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.

    Good for: Hydrating

  • Matrixyl PeptidesModerate evidenceFull dossier ↗

    Signals your skin to make more collagen. Quiet but real support for firmness and fine lines with consistent daily use.

    Good for: Anti-aging

  • NiacinamideStrong evidenceFull dossier ↗

    A multitasker that calms redness, evens out skin tone, and helps oily skin balance out. One of the safest do-a-little-of-everything ingredients.

    Good for: Brightening, Barrier repair, Anti-inflammatory

  • Shea ButterModerate evidenceFull dossier ↗

    A rich, naturally occlusive plant butter from the African karite tree. Soothes dry, irritation-prone skin, refills the lipid barrier, and was well tolerated enough in randomized trials that most participants used it comfortably as a daily emollient.

    Good for: Barrier repair, Hydrating, Anti-inflammatory

Evidence behind the ingredients

Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.

AdenosineModerate evidence6 citations

A Korean-approved anti-wrinkle ingredient that encourages collagen production for a smoother, firmer look.

Yang HJ et al., Two-phase delivery using a horse oil and adenosine-loaded dissolving microneedle patch for skin barrier restoration, moisturization, and wrinkle improvement, Journal of Cosmetic Dermatology 2019;18(3):936-943 — Korean clinical study (n=20): adenosine microneedle patches improved elasticity, hydration, dermal density, wrinkles

2019Positive (efficacy)PMID:30160014View source ↗

Kang G et al., Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration, International Journal of Cosmetic Science 2018;40(2):199-206 — Korean-authored; adenosine microneedle patches matched or exceeded adenosine cream for multiple endpoints

2018Positive (efficacy)PMID:29574973View source ↗

Kim MY et al., Effect of adenosine on melanogenesis in B16 cells and zebrafish, Annals of Dermatology 2014;26(2):209-13 — adenosine suppresses pigmentation via negative regulation of tyrosinase in cellular and zebrafish models

2014Mechanism onlyPMID:24882976View source ↗
Argan OilModerate evidence4 citations

The Moroccan kitchen-staple oil with real cosmetic data behind it. Daily use measurably improves skin elasticity in postmenopausal women. Good for dry, mature, or barrier-compromised skin without feeling greasy.

Lin TK, Zhong L, Santiago JL, Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils, International Journal of Molecular Sciences 2017;19(1):70 — review of 19 plant oils including argan: documents anti-inflammatory, antioxidant, stratum-corneum barrier-repair mechanisms

2017Mechanism onlyPMID:29280987View source ↗

Boucetta KQ et al., The effect of dietary and/or cosmetic argan oil on postmenopausal skin elasticity, Clinical Interventions in Aging 2015;10:339-349 — 60-day RCT: both dietary and topical argan oil significantly increased cutometer-measured gross, net, and biological elasticity (all p<0.001) vs olive oil control

2015Positive (efficacy)PMID:25673976View source ↗

Boucetta KQ et al., Skin hydration in postmenopausal women: argan oil benefit with oral and/or topical use, Przeglad Menopauzalny 2014;13(5):280-288 — RCT; topical forearm application over 60 days significantly improved skin hydration

2014Positive (efficacy)PMID:26327867View source ↗
ArgirelineModerate evidence6 citations

Sometimes called "topical Botox," it's a peptide that subtly reduces the depth of expression lines around the eyes and forehead when used daily over months. Mild effect, but real.

Zhu M et al., The effect of a serum containing acetyl hexapeptide-8, dipeptide diaminobutyroyl benzylamide diacetate and gluconolactone on skin biomarkers, wrinkles and skin texture: ex vivo and clinical studies, International Journal of Cosmetic Science 2026 — two clinical trials (n=50, n=42) showed 35-69% static wrinkle improvement and significant elastic fiber and collagen biomarker increases at 12 weeks

2026Positive (efficacy)PMID:41668671View source ↗

Zdrada-Nowak J, Surgiel-Gemza A, Szatkowska M, Acetyl Hexapeptide-8 in Cosmeceuticals: A Review of Skin Permeability and Efficacy, International Journal of Molecular Sciences 2025

2025InconclusivePMID:40565185View source ↗

Henseler H, Investigating the effects of Argireline in a skin serum containing hyaluronic acids on skin surface wrinkles using the Visia Complexion Analysis camera system, GMS Interdisciplinary Plastic and Reconstructive Surgery DGPW 2023;12:Doc09 — topical argireline serum reduced measured surface wrinkles

2023Positive (efficacy)PMID:38024099View source ↗
+7 more ingredients
BeeswaxModerate evidence4 citations

A wax film former that quietly does what petrolatum does (slows water loss and shields chapped skin) without feeling slick. Most evidence comes from honey/beeswax/olive-oil cerates that have shown improvement in dry, irritation-prone skin in controlled trials. CIR-affirmed safe.

Souza C et al., Topical Formulation Containing Beeswax-Based Nanoparticles Improved In Vivo Skin Barrier Function, AAPS PharmSciTech 2017;18(7):2505-2516 — controlled: beeswax-based nanoparticle topical formulation

2017Positive (efficacy)PMID:28213845View source ↗

Al-Waili NS. Clinical and mycological benefits of topical application of honey, olive oil and beeswax in diaper dermatitis. Clin Microbiol Infect. 2005;11(2):160-163.

2005Positive (efficacy)PMID:15679495View source ↗

CIR Expert Panel. Safety Assessment of Beeswax, Candelilla Wax, Carnauba Wax, Japan Wax, and Beeswax-Derived Ingredients. Int J Toxicol. (Reaffirmed 2005.)

2005Safety assessmentDOI:10.3109/10915818409010515View source ↗
Copper PeptidesModerate evidence7 citations

A signal peptide that tells your skin to make more collagen and elastin. Quiet but consistent firmness support over months of daily use.

Patel MN et al., An Assessment of the Safety, Efficacy, and Tolerability of a Novel Scalp Treatment Regimen Combining a Hydroxy Acid-Based Scrub and Copper Tripeptide Serum in the Management of Seborrheic Dermatitis in Adults, Cureus 2024;16(9):e70108 — 15-day interventional study: copper tripeptide regimen reduced flaking, improved hydration in seborrheic dermatitis

2024Positive (efficacy)PMID:39449909View source ↗

Jiang F et al., Synergy of GHK-Cu and hyaluronic acid on collagen IV upregulation via fibroblast and ex-vivo skin tests, Journal of Cosmetic Dermatology 2023;22(9):2598-2604 — in vitro + ex vivo: GHK-Cu + HA promoted collagen I, IV, and VII; 25.4-fold collagen IV increase in fibroblasts

2023Mechanism onlyPMID:37062921View source ↗

Dou Y et al., The potential of GHK as an anti-aging peptide, Aging Pathobiology and Therapeutics 2020;2(1):58-61 — narrative review of GHK-Cu's anti-inflammatory and tissue-remodeling mechanisms

2020Mechanism onlyPMID:35083444View source ↗
DimethiconeStrong evidence5 citations

A silicone that sits on your skin as an invisible, non-greasy shield. Reduces water loss, protects against irritants (think soap, friction, incontinence), and is FDA-recognised as a skin protectant from 1-30%. The reason your favourite primer feels silky and your barrier cream actually works under makeup.

Beeckman D, Verhaeghe S, Defloor T, et al. A 3-in-1 perineal care washcloth impregnated with dimethicone 3% versus water and pH neutral soap to prevent and treat incontinence-associated dermatitis: a randomized, controlled clinical trial. J Wound Ostomy Continence Nurs. 2011;38(6):627-634.

2011Positive (efficacy)PMID:21952346View source ↗

Saary J, Qureshi R, Palda V, et al. A systematic review of contact dermatitis treatment and prevention. J Am Acad Dermatol. 2005;53(5):845-855. (Barrier creams containing dimethicone prevent irritant contact dermatitis.)

2005Meta-analysis (positive)PMID:16243136View source ↗

FDA OTC Final Monograph, 21 CFR Part 347 — Skin Protectant Drug Products for Over-the-Counter Human Use; dimethicone listed at section 347.10 as a Category I active ingredient at 1-30%.

2003Regulatory approval21CFR347.10View source ↗
GlycerinModerate evidence6 citations

A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.

Danby SG et al., Different types of emollient cream exhibit diverse physiological effects on the skin barrier in adults with atopic dermatitis, Clinical and Experimental Dermatology 2022;47(6):1154-1164 — glycerol+urea emollient delivered superior barrier-strengthening and irritant protection

2022Positive (efficacy)PMID:35167133View source ↗

Youssef R et al., Glycerol 85% efficacy on atopic skin and its microbiome: a randomized controlled trial, Journal of Dermatological Treatment 2021;32(7):730-736 — topical glycerol 85% RCT on atopic skin

2021Positive (efficacy)PMID:31869257View source ↗

Evans NJ et al., Human axillary skin condition is improved following incorporation of glycerol into the stratum corneum from an antiperspirant formulation, Archives of Dermatological Research 2017;309(9):739-748 — 4% glycerol penetrated axillary SC, reduced irritation, improved hydration

2017Positive (efficacy)PMID:28889318View source ↗
Matrixyl PeptidesModerate evidence6 citations

Signals your skin to make more collagen. Quiet but real support for firmness and fine lines with consistent daily use.

Yang Y et al., Comprehensive evaluation of the efficacy and safety of a new multi-component anti-aging topical eye cream, Skin Research and Technology 2024;30(7):e13790 — 12-week study of active complex containing Matrixyl 3000 peptides showed significant improvement in hydration, elasticity, periorbital wrinkles

2024Positive (efficacy)PMID:38932444View source ↗

Aruan RR et al., Double-blind, Randomized Trial on the Effectiveness of Acetylhexapeptide-3 Cream and Palmitoyl Pentapeptide-4 Cream for Crow's Feet, Journal of Clinical and Aesthetic Dermatology 2023;16(2):37-43 — RCT of topical palmitoyl pentapeptide-4 (Matrixyl) for periorbital wrinkles

2023Positive (efficacy)PMID:36909866View source ↗

Imhof L, Leuthard D, Topical Over-the-Counter Antiaging Agents: An Update and Systematic Review, Dermatology 2021;237(2):217-229 — SR covering topical antiaging peptides

2021Meta-analysis (positive)PMID:32882685View source ↗
NiacinamideStrong evidence10 citations

A multitasker that calms redness, evens out skin tone, and helps oily skin balance out. One of the safest do-a-little-of-everything ingredients.

Moro F et al., Skin Cancer Prevention and Antiaging: Role of Nicotinamide, International Journal of Molecular Sciences 2026

2026Mechanism onlyPMID:42278444View source ↗

Passeron T et al., An Investigator-Blinded, Randomized Trial of a Broad-Spectrum Sunscreen Containing Sclareolide and Niacinamide, Dermatology and Therapy (Heidelberg) 2026

2026Positive (efficacy)PMID:41240206View source ↗

Vergilio MM et al., Topical Formulation with Niacinamide Combined with 5 MHz Ultrasound for Improving Skin Ageing, Current Medicinal Chemistry 2025

2025Positive (efficacy)PMID:39171587View source ↗
Shea ButterModerate evidence4 citations

A rich, naturally occlusive plant butter from the African karite tree. Soothes dry, irritation-prone skin, refills the lipid barrier, and was well tolerated enough in randomized trials that most participants used it comfortably as a daily emollient.

O'Connor RJ et al., Clinical Evaluation of a Diaper Containing a Shea Butter-Based Emollient and Impact on Diapered Skin Erythema, Pediatr Dermatol 2025;42(3):532-538 — RCT n=271 infants, shea-butter diaper reduced dermatitis

2025Positive (efficacy)PMID:40189822View source ↗

Burnett CL, Bergfeld WF, Belsito DV, et al. Safety Assessment of Butyrospermum parkii (Shea)-Derived Ingredients as Used in Cosmetics. Cosmetic Ingredient Review Expert Panel Final Report.

2024Safety assessmentDOI:10.1177/10915818231224230View source ↗

Verallo-Rowell VM, Katalbas SS, Pangasinan JP. Natural (Mineral, Vegetable, Coconut, Essential) Oils and Contact Dermatitis. Curr Allergy Asthma Rep. 2016;16(7):51. — discussing shea butter unsaponifiable fraction NF-kB inhibition and dermatologic use.

2016Mechanism onlyPMID:27373890View source ↗

Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.

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