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Shop pHisoderm Ph Clinical For Blemish-Prone Skin
Moisturizer
pHisoderm

Ph Clinical For Blemish-Prone Skin

~$30· 6 Fl Oz (Pack of 4)

What it's good for

Key actives from our research database. Click any to read the full evidence dossier.

  • Aloe VeraModerate evidenceFull dossier ↗

    Calms irritation and adds light hydration. The classic for sunburned or reactive skin.

    Good for: Anti-inflammatory, Hydrating

  • Citric AcidModerate evidenceFull dossier ↗

    A fruit-derived AHA that exfoliates and antioxidizes. It shares the same basic mechanism as glycolic and lactic acid but is weaker gram-for-gram; in practice you'll see it doing dual duty (a little exfoliation plus pH stabilisation) in multi-acid toners and serums. When it appears low on an ingredient list, it's adjusting pH; higher up, it's contributing real exfoliation.

    Good for: Exfoliating, Antioxidant

  • GlycerinModerate evidenceFull dossier ↗

    A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.

    Good for: Hydrating

  • PetrolatumStrong evidenceFull dossier ↗

    The gold-standard occlusive moisturiser. Locks water into damaged or compromised skin better than anything else, accelerates barrier repair, and (in newer research) actively boosts your skin's own antimicrobial defences. Cheap, non-allergenic, widely recommended by dermatologists for very dry, compromised, or post-procedure skin and for slugging.

    Good for: Barrier repair, Hydrating

New to this? Patch test on your inner arm for 24 to 48 hours before applying to your face. If you have sensitive skin or rosacea, start 2 to 3 times per week and build up slowly.

Evidence behind the ingredients

Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.

Aloe VeraModerate evidence7 citations

Calms irritation and adds light hydration. The classic for sunburned or reactive skin.

Huang YN et al., Effects of Aloe vera on Burn Injuries: A Systematic Review and Meta-Analysis of Randomized Controlled Trials, Journal of Burn Care & Research 2024;45(6):1536-1545 — topical aloe vera reduced burn wound-healing time

2024Meta-analysis (positive)PMID:38605441View source ↗

Tungkasamit T et al., Reduction in severity of radiation-induced dermatitis in head and neck cancer patients treated with topical aloe vera gel: A randomized multicenter double-blind placebo-controlled trial, European Journal of Oncology Nursing 2022;59:102164 — aloe vera reduced severity of moderate-to-severe radiation dermatitis

2022Positive (efficacy)PMID:35767935View source ↗

Sharma S et al., Second-Degree Burns and Aloe Vera: A Meta-analysis and Systematic Review, Advances in Skin & Wound Care 2022;35(11):1-9 — topical aloe vera shortened time to healing for second-degree burns

2022Meta-analysis (positive)PMID:36264753View source ↗
Citric AcidModerate evidence4 citations

A fruit-derived AHA that exfoliates and antioxidizes. It shares the same basic mechanism as glycolic and lactic acid but is weaker gram-for-gram; in practice you'll see it doing dual duty (a little exfoliation plus pH stabilisation) in multi-acid toners and serums. When it appears low on an ingredient list, it's adjusting pH; higher up, it's contributing real exfoliation.

Tang SC, Yang JH. Dual Effects of Alpha-Hydroxy Acids on the Skin. Molecules. 2018;23(4):863.

2018Mechanism onlyPMC:PMC6017965View source ↗

Yamamoto Y, Uede K, Yonei N, Kishioka A, Ohtani T, Furukawa F. Effects of alpha-hydroxy acids on the human skin of Japanese subjects: the rationale for chemical peeling. Journal of Dermatology. 2006 Jan;33(1):16-22. — Clinical-mechanistic study in Japanese subjects demonstrating AHA (including citric acid class) keratolytic and epidermal renewal effects as rationale for chemical peeling.

2006Mechanism onlyPMID:16469079View source ↗

Bernstein EF, Underhill CB, Lakkakorpi J, et al. Citric acid increases viable epidermal thickness and glycosaminoglycan content of sun-damaged skin. Dermatologic Surgery. 1997 Aug;23(8):689-694. — Mechanistic study showing topical citric acid increased viable epidermal thickness and dermal glycosaminoglycans in sun-damaged skin, similar to glycolic acid and retinoic acid.

1997Mechanism onlyPMID:9256916View source ↗
GlycerinModerate evidence6 citations

A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.

Danby SG et al., Different types of emollient cream exhibit diverse physiological effects on the skin barrier in adults with atopic dermatitis, Clinical and Experimental Dermatology 2022;47(6):1154-1164 — glycerol+urea emollient delivered superior barrier-strengthening and irritant protection

2022Positive (efficacy)PMID:35167133View source ↗

Youssef R et al., Glycerol 85% efficacy on atopic skin and its microbiome: a randomized controlled trial, Journal of Dermatological Treatment 2021;32(7):730-736 — topical glycerol 85% RCT on atopic skin

2021Positive (efficacy)PMID:31869257View source ↗

Evans NJ et al., Human axillary skin condition is improved following incorporation of glycerol into the stratum corneum from an antiperspirant formulation, Archives of Dermatological Research 2017;309(9):739-748 — 4% glycerol penetrated axillary SC, reduced irritation, improved hydration

2017Positive (efficacy)PMID:28889318View source ↗
+1 more ingredient
PetrolatumStrong evidence7 citations

The gold-standard occlusive moisturiser. Locks water into damaged or compromised skin better than anything else, accelerates barrier repair, and (in newer research) actively boosts your skin's own antimicrobial defences. Cheap, non-allergenic, widely recommended by dermatologists for very dry, compromised, or post-procedure skin and for slugging.

van Zuuren EJ, Fedorowicz Z, Christensen R, Lavrijsen APM, Arents BWM. Emollients and moisturisers for eczema. Cochrane Database Syst Rev. 2017;2:CD012119. — Cochrane review of 77 studies (n=6,603) found most moisturisers prolonged time to flare, reduced flares, and reduced topical corticosteroid use; moisturisers combined with active treatment outperformed active treatment alone.

2017Meta-analysis (positive)PMID:28166390View source ↗

Czarnowicki T, Malajian D, Khattri S, et al. Petrolatum: Barrier repair and antimicrobial responses underlying this 'inert' moisturizer. J Allergy Clin Immunol. 2016;137(4):1091-1102.e7.

2016Mechanism onlyPMID:26431582View source ↗

Genuino GAS, Baluyut-Angeles KV, Espiritu APT, Lapitan MCM, Buckley BS. Topical petrolatum gel alone versus topical silver sulfadiazine with standard gauze dressings for the treatment of superficial partial thickness burns in adults: a randomized controlled trial. Burns. 2014;40(7):1267-1273. — RCT: petrolatum gel at least as effective as silver sulfadiazine for re-epithelialization (mean 6.2 vs 7.8 days) with similar infection/allergy rates.

2014Positive (efficacy)PMID:25172229View source ↗

Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.

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Not medical advice. GlowPal is educational. Patch-test new products and talk to a qualified healthcare professional before changing your routine, especially if you're pregnant, nursing, or have a diagnosed skin condition. See our terms.