Shop Thayers Blemish Clearing Acne Pads with 2% Salicylic Acid and Witch Hazel (60 Count)
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Thayers

Blemish Clearing Acne Pads with 2% Salicylic Acid and Witch Hazel (60 Count)

~$16
AcneDrynessVisible pores

Tracked ingredients

Key actives from our research database. Click any to read the full evidence dossier.

Evidence behind the ingredients

Real citations from our research database — one per tracked active in this product. Click any ingredient name to read its full evidence dossier.

Salicylic AcidStrong evidence7 citations

Goes into your pores and dissolves the oil and dead skin clogging them. Best for blackheads, whiteheads, and oily, acne-prone skin.

Liu Y et al., Clinical Efficacy of a Salicylic Acid-Containing Gel on Acne Management and Skin Barrier Function: A 21-Day Prospective Study, Journal of Cosmetic Dermatology 2025;24(7):e70353 — salicylic acid gel reduced acne lesions, regulated sebum, improved hydration and barrier function

2025Positive — efficacyPMID:40682377View source ↗

Ye R et al., 2% supramolecular salicylic acid hydrogel vs. adapalene gel in mild to moderate acne vulgaris: multicenter, randomized, evaluator-blind, parallel-controlled trial, Journal of Cosmetic Dermatology 2024;23(6):2125-2134 — 2% SSA hydrogel was equally effective as adapalene gel for mild-to-moderate acne

2024Positive — efficacyPMID:38590107View source ↗

Liu H et al., Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid for acne, Cochrane Database of Systematic Reviews 2020;5:CD011368 — conclusion: clinical benefit is unclear

2020Meta-analysis — mixedPMID:32356369View source ↗
Aloe VeraModerate evidence5 citations

Calms irritation and adds light hydration. The classic for sunburned or reactive skin.

Tungkasamit T et al., Reduction in severity of radiation-induced dermatitis in head and neck cancer patients treated with topical aloe vera gel: A randomized multicenter double-blind placebo-controlled trial, European Journal of Oncology Nursing 2022;59:102164 — aloe vera reduced severity of moderate-to-severe radiation dermatitis

2022Positive — efficacyPMID:35767935View source ↗

Hekmatpou D et al., The effect of aloe vera clinical trials on prevention and healing of skin wound: a systematic review, Iranian Journal of Medical Sciences 2019;44(1):1-9

2019Meta-analysis — positivePMID:30666070View source ↗

Burusapat C et al., Topical Aloe Vera Gel for Accelerated Wound Healing of Split-Thickness Skin Graft Donor Sites: A Double-Blind, Randomized, Controlled Trial and Systematic Review, Plastic and Reconstructive Surgery 2018;142(1):217-226 — aloe vera gel shortened donor-site reepithelialization to 11.5 vs 13.7 days

2018Positive — efficacyPMID:29649056View source ↗
Tea Tree OilModerate evidence4 citations

A natural acne spot-treatment that kills the bacteria behind red, painful pimples. Slower than benzoyl peroxide but with fewer side effects when used at 5%.

Najafi-Taher R et al., A topical gel of tea tree oil nanoemulsion containing adapalene versus adapalene marketed gel in patients with acne vulgaris: a randomized clinical trial, Archives of Dermatological Research 2022;314(7):673-679 — RCT showed tea tree oil + adapalene nanoemulsion gel produced significantly better reduction in total, inflammatory and non-inflammatory acne lesions than standard adapalene

2022Positive — efficacyPMID:34251536View source ↗

Malhi HK, Tu J, Riley TV, Kumarasinghe SP, Hammer KA, Tea tree oil gel for mild to moderate acne; a 12 week uncontrolled, open-label phase II pilot study, Australasian Journal of Dermatology 2017;58(3):205-210

2017Positive — efficacyPMID:27000386View source ↗

Enshaieh S, Jooya A, Siadat AH, Iraji F, The efficacy of 5% topical tea tree oil gel in mild to moderate acne vulgaris: a randomized, double-blind placebo-controlled study, Indian Journal of Dermatology Venereology and Leprology 2007;73(1):22-5

2007Positive — efficacyPMID:17314442View source ↗
+1 more ingredient
GlycerinModerate evidence4 citations

A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.

Danby SG et al., Different types of emollient cream exhibit diverse physiological effects on the skin barrier in adults with atopic dermatitis, Clinical and Experimental Dermatology 2022;47(6):1154-1164 — glycerol+urea emollient delivered superior barrier-strengthening and irritant protection

2022Positive — efficacyPMID:35167133View source ↗

Evans NJ et al., Human axillary skin condition is improved following incorporation of glycerol into the stratum corneum from an antiperspirant formulation, Archives of Dermatological Research 2017;309(9):739-748 — 4% glycerol penetrated axillary SC, reduced irritation, improved hydration

2017Positive — efficacyPMID:28889318View source ↗

Fluhr JW et al., Glycerol and the skin: holistic approach to its origin and functions, British Journal of Dermatology 2008;159(1):23-34 — improves xerosis and barrier function

2008Positive — efficacyPMID:18510666View source ↗

Sources: PubMed · KCI · J-Stage · CNKI · Wanfang · SFD · MFDS · Cochrane · SCCS · CIR. Every entry points to a specific document. See methodology for what each outcome label means.

Layering conflicts

Ingredients in this product that can react with common actives. Avoid stacking unless noted.

  • Retinol + salicylic acid can over-exfoliate and damage the barrier. Alternate nights.

  • Tretinoin + salicylic acid — major irritation risk. Strict separation required.

  • AHA + BHA stacking risks over-exfoliation. Use a pre-formulated AHA/BHA product or alternate days.

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