Shop TIRTIR Collagen Lifting Eye Cream
Treatment
TIRTIR

Collagen Lifting Eye Cream

~$35· 15ml / 0.5 fl oz
Fine lines & firmnessDrynessRadiance

Evidence behind the ingredients

Real citations from our research database — one per tracked active in this product. Click any ingredient name to read its full evidence dossier.

Hydrolyzed CollagenModerate evidence3 citations

The protein your skin loses with age, broken down small enough to absorb. Multiple meta-analyses of RCTs show measurable wins in wrinkles, elasticity, and hydration after ~12 weeks. Most evidence is oral, but topical helps surface hydration too.

Pu SY et al., Effects of Oral Collagen for Skin Anti-Aging: A Systematic Review and Meta-Analysis, Nutrients 2023;15(9):2080 — 26 RCTs / 1,721 patients: hydrolyzed collagen significantly improved skin hydration and elasticity vs placebo across multiple collagen sources

2023Meta-analysis — positivePMID:37432180View source ↗

de Miranda RB, Weimer P, Rossi RC, Effects of hydrolyzed collagen supplementation on skin aging: a systematic review and meta-analysis, International Journal of Dermatology 2021 — 19 RCTs / 1,125 participants: 90-day oral hydrolyzed collagen significantly reduced wrinkles and improved skin elasticity and hydration vs placebo

2021Meta-analysis — positivePMID:33742704View source ↗

Evans M et al., A randomized triple-blind placebo-controlled parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity, Journal of Cosmetic Dermatology 2021;20(3):825-834 — 12-week RCT: ~35% reduction in wrinkle scores and improved elasticity vs placebo

2021Positive — efficacyPMID:32799362View source ↗
Matrixyl PeptidesModerate evidence7 citations

Signals your skin to make more collagen. Quiet but real support for firmness and fine lines with consistent daily use.

Yang Y et al., Comprehensive evaluation of the efficacy and safety of a new multi-component anti-aging topical eye cream, Skin Research and Technology 2024;30(7):e13790 — 12-week study of active complex containing Matrixyl 3000 peptides showed significant improvement in hydration, elasticity, periorbital wrinkles

2024Positive — efficacyPMID:38932444View source ↗

Lintner K, Gerstein F, Solish N, A serum containing vitamins C and E and a matrix-repair tripeptide reduces facial signs of aging as evidenced by Primos analysis, Journal of Cosmetic Dermatology 2020;19(12):3262-3269 — matrix-repair tripeptide serum: 8-9% roughness reduction, 9% redness reduction by Primos imaging

2020Positive — efficacyPMID:33103342View source ↗

MFDS Notified Functional Cosmetic Active — Palmitoyl Pentapeptide-4 / Matrixyl (anti-wrinkle, adjunct claim). Korean Ministry of Food and Drug Safety, Cosmetic Functional Active Ingredient List. NOTE: this codex listing should be re-verified — official MFDS anti-wrinkle codex traditionally lists Retinol/Retinyl Palmitate/Polyethoxylated Retinamide/Adenosine; Matrixyl inclusion needs independent confirmation.

2020Regulatory approvalMFDS:Matrixyl-AntiWrinkleView source ↗
NiacinamideStrong evidence8 citations

A multitasker that calms redness, evens out skin tone, and helps oily skin balance out. One of the safest do-a-little-of-everything ingredients.

Korean authors et al., Anti-acne and Tolerance Assessment of a Cleanser Containing Salicylic Acid, Gluconolactone and Niacinamide, Asian Journal of Beauty and Cosmetology 2024;22(3):383-391 — 4-week clinical trial (n=43 oily acne-prone): significant reduction in inflammatory + non-inflammatory acne lesions and sebum content; 2-week safety (n=39 sensitive skin) confirmed tolerance

2024Positive — efficacyKCI:ART003120116View source ↗

Korean authors et al., A split-face study to evaluate the efficacy of a dissolving microneedle-encapsulated niacinamide skin patch for the reduction of facial hyperpigmentation, Archives of Aesthetic Plastic Surgery 2022;28(4):113-118 — 17-patient 2-week split-face RCT: DMN niacinamide patch significantly reduced epidermal pigmentation score and melanin score vs untreated control side

2022Positive — efficacyKCI:ART002889427View source ↗

Liu H et al., Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne, Cochrane Database of Systematic Reviews 2020;5:CD011368 — conclusion: clinical benefit is unclear

2020Meta-analysis — mixedPMID:32356369View source ↗
+2 more ingredients
AdenosineModerate evidence6 citations

A Korean-approved anti-wrinkle ingredient that encourages collagen production for a smoother, firmer look.

MFDS Approved Functional Cosmetic Active — Adenosine (anti-wrinkle). Korean Ministry of Food and Drug Safety, Cosmetic Functional Active Ingredient List

2020Regulatory approvalMFDS:Adenosine-AntiWrinkleView source ↗

Jang M et al., Dissolving microneedle with high molecular weight hyaluronic acid to improve skin wrinkles, dermal density and elasticity, International Journal of Cosmetic Science 2020;42(3):302-309 — Korean comparison: HMW HA + adenosine outperformed LMW HA across wrinkle and elasticity parameters

2020Positive — efficacyPMID:32421218View source ↗

Yang HJ et al., Two-phase delivery using a horse oil and adenosine-loaded dissolving microneedle patch for skin barrier restoration, moisturization, and wrinkle improvement, Journal of Cosmetic Dermatology 2019;18(3):936-943 — Korean clinical study (n=20): adenosine microneedle patches improved elasticity, hydration, dermal density, wrinkles

2019Positive — efficacyPMID:30160014View source ↗
GlycerinModerate evidence4 citations

A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.

Danby SG et al., Different types of emollient cream exhibit diverse physiological effects on the skin barrier in adults with atopic dermatitis, Clinical and Experimental Dermatology 2022;47(6):1154-1164 — glycerol+urea emollient delivered superior barrier-strengthening and irritant protection

2022Positive — efficacyPMID:35167133View source ↗

Evans NJ et al., Human axillary skin condition is improved following incorporation of glycerol into the stratum corneum from an antiperspirant formulation, Archives of Dermatological Research 2017;309(9):739-748 — 4% glycerol penetrated axillary SC, reduced irritation, improved hydration

2017Positive — efficacyPMID:28889318View source ↗

Fluhr JW et al., Glycerol and the skin: holistic approach to its origin and functions, British Journal of Dermatology 2008;159(1):23-34 — improves xerosis and barrier function

2008Positive — efficacyPMID:18510666View source ↗

Sources: PubMed · KCI · J-Stage · CNKI · Wanfang · SFD · MFDS · Cochrane · SCCS · CIR. Every entry points to a specific document. See methodology for what each outcome label means.

Layering conflicts

Ingredients in this product that can react with common actives. Avoid stacking unless noted.

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