Calendula Sleeping Mask
What it's good for
Key actives from our research database. Click any to read the full evidence dossier.
Sometimes called "topical Botox," it's a peptide that subtly reduces the depth of expression lines around the eyes and forehead when used daily over months. Mild effect, but real.
Good for: Anti-aging
A botanical with real clinical wins for irritated, post-procedure, or recovering skin, with randomized-trial support behind its soothing reputation. Gentle enough for delicate, easily reactive skin and dry, sensitive patches.
Good for: Anti-inflammatory
Also called "cica," it calms redness, repairs the skin barrier, and speeds up recovery. The go-to for irritated or reactive skin.
Good for: Anti-inflammatory, Barrier repair
Refills the natural barrier between your skin cells. Locks moisture in, keeps irritants out, calms dry or damaged skin.
Good for: Barrier repair
The classic "tea-bag-on-puffy-eyes" botanical. Calms angry skin via well-studied anti-inflammatory pathways, gently. Good for reactive or rosacea-prone complexions.
Good for: Anti-inflammatory, Antioxidant
A signal peptide that tells your skin to make more collagen and elastin. Quiet but consistent firmness support over months of daily use.
Good for: Anti-aging
A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.
Good for: Hydrating
A pure hydrator that holds water in your skin. Makes skin look plumper and smoother almost immediately.
Good for: Hydrating
Signals your skin to make more collagen. Quiet but real support for firmness and fine lines with consistent daily use.
Good for: Anti-aging
Pro-vitamin B5. Deeply hydrates and helps repair the skin barrier, calming dry or compromised skin.
Good for: Hydrating, Barrier repair
A workhorse antioxidant that defends your skin from daily oxidative damage. Pairs especially well with vitamin C, and it's in nearly every good moisturizer for a reason.
Good for: Antioxidant
Evidence behind the ingredients
Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.
Sometimes called "topical Botox," it's a peptide that subtly reduces the depth of expression lines around the eyes and forehead when used daily over months. Mild effect, but real.
Zhu M et al., The effect of a serum containing acetyl hexapeptide-8, dipeptide diaminobutyroyl benzylamide diacetate and gluconolactone on skin biomarkers, wrinkles and skin texture: ex vivo and clinical studies, International Journal of Cosmetic Science 2026 — two clinical trials (n=50, n=42) showed 35-69% static wrinkle improvement and significant elastic fiber and collagen biomarker increases at 12 weeks
Zdrada-Nowak J, Surgiel-Gemza A, Szatkowska M, Acetyl Hexapeptide-8 in Cosmeceuticals: A Review of Skin Permeability and Efficacy, International Journal of Molecular Sciences 2025
Henseler H, Investigating the effects of Argireline in a skin serum containing hyaluronic acids on skin surface wrinkles using the Visia Complexion Analysis camera system, GMS Interdisciplinary Plastic and Reconstructive Surgery DGPW 2023;12:Doc09 — topical argireline serum reduced measured surface wrinkles
A botanical with real clinical wins for irritated, post-procedure, or recovering skin, with randomized-trial support behind its soothing reputation. Gentle enough for delicate, easily reactive skin and dry, sensitive patches.
Deligiannidou GE et al. (Greece), An Update of Phytotherapeutic Advances of Marigold (Calendula officinalis L.) in Wound Healing, Plants (Basel) 2025 — peer-reviewed review of 2020-2025 experimental and clinical evidence on Calendula formulations for skin regeneration: healing rate, cell proliferation, inflammatory modulation
Effect of oral Calendula officinalis on second-degree burn wound healing (Iran), Scars Burns and Healing 2023
Siddiquee S et al., Efficacy of topical Calendula officinalis on prevalence of radiation-induced dermatitis: A randomised controlled trial, Australasian Journal of Dermatology 2021;62(1):e35-e40 — topical calendula reduced radiation-induced dermatitis
Also called "cica," it calms redness, repairs the skin barrier, and speeds up recovery. The go-to for irritated or reactive skin.
Hur N et al., A Randomized, Double-Blind, Placebo-Controlled Trial Assessing the Effects of Oral Centella asiatica Extract on Skin Aging-Related Parameters in Middle-Aged Korean Women, Nutrients 2026
Borowicz KK et al., Geroprotective Potential of Centella asiatica: Modulation of Cellular Aging, Nutrients 2026
Witkowska K et al., Topical Application of Centella asiatica in Wound Healing: Recent Insights into Mechanisms and Clinical Efficacy, Pharmaceutics 2024;16(10):1252 — modern hydrogel and nanostructured Centella delivery systems accelerate wound healing across wound types
+−8 more ingredients
Refills the natural barrier between your skin cells. Locks moisture in, keeps irritants out, calms dry or damaged skin.
Andrew PV et al., Topical supplementation with physiological lipids rebalances the stratum corneum ceramide profile and strengthens skin barrier function in adults predisposed to atopic dermatitis, British Journal of Dermatology 2025;193(4):729-740 — physiological-lipid emulsion raised SC ceramide NP/AP and improved barrier function vs control
Nugroho WT, Sawitri, Astindari, Utomo B, Listiawan MY, Ervianti E, Astari L. The Efficacy of Moisturisers Containing Ceramide Compared with Other Moisturisers in the Management of Atopic Dermatitis: A Systematic Literature Review and Meta-Analysis. Indian J Dermatol. 2023;68(1):53-58. — Meta-analysis of 5 studies found ceramide-containing moisturisers produced significantly greater improvement in SCORAD compared with non-ceramide moisturisers in atopic dermatitis.
Shindo S et al., Effects of a moisturizer containing pseudo-ceramide and a eucalyptus extract on sweating function in adult atopic dermatitis: a double-blind, randomized, controlled left-right comparison clinical trial, Journal of Cosmetic Dermatology 2022;21(10):4503-4509 — pseudo-ceramide + eucalyptus moisturizer restored sweating function and barrier in AD adults
The classic "tea-bag-on-puffy-eyes" botanical. Calms angry skin via well-studied anti-inflammatory pathways, gently. Good for reactive or rosacea-prone complexions.
Essential Oil of Matricaria chamomilla Alleviates Psoriatic-Like Skin Inflammation by Inhibiting PI3K/Akt/mTOR and p38MAPK Signaling Pathway, Clinical Cosmetic and Investigational Dermatology 2024
Comparative analysis of whole plant, flower and root extracts of Chamomilla recutita L. (Germany), Frontiers in Immunology 2024
Xu J et al., Therapeutic effects of chamomile volatile oil nanoemulsion/Bletilla striata polysaccharides gels on atopic dermatitis, International Journal of Biological Macromolecules 2024 — topical chamomile volatile oil nanoemulsion (19.07 nm) reduced skin damage, epidermal thickness, and mast cell infiltration in atopic dermatitis mice; rebalanced Th1/Th2
A signal peptide that tells your skin to make more collagen and elastin. Quiet but consistent firmness support over months of daily use.
Patel MN et al., An Assessment of the Safety, Efficacy, and Tolerability of a Novel Scalp Treatment Regimen Combining a Hydroxy Acid-Based Scrub and Copper Tripeptide Serum in the Management of Seborrheic Dermatitis in Adults, Cureus 2024;16(9):e70108 — 15-day interventional study: copper tripeptide regimen reduced flaking, improved hydration in seborrheic dermatitis
Jiang F et al., Synergy of GHK-Cu and hyaluronic acid on collagen IV upregulation via fibroblast and ex-vivo skin tests, Journal of Cosmetic Dermatology 2023;22(9):2598-2604 — in vitro + ex vivo: GHK-Cu + HA promoted collagen I, IV, and VII; 25.4-fold collagen IV increase in fibroblasts
Dou Y et al., The potential of GHK as an anti-aging peptide, Aging Pathobiology and Therapeutics 2020;2(1):58-61 — narrative review of GHK-Cu's anti-inflammatory and tissue-remodeling mechanisms
A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.
Danby SG et al., Different types of emollient cream exhibit diverse physiological effects on the skin barrier in adults with atopic dermatitis, Clinical and Experimental Dermatology 2022;47(6):1154-1164 — glycerol+urea emollient delivered superior barrier-strengthening and irritant protection
Youssef R et al., Glycerol 85% efficacy on atopic skin and its microbiome: a randomized controlled trial, Journal of Dermatological Treatment 2021;32(7):730-736 — topical glycerol 85% RCT on atopic skin
Evans NJ et al., Human axillary skin condition is improved following incorporation of glycerol into the stratum corneum from an antiperspirant formulation, Archives of Dermatological Research 2017;309(9):739-748 — 4% glycerol penetrated axillary SC, reduced irritation, improved hydration
A pure hydrator that holds water in your skin. Makes skin look plumper and smoother almost immediately.
Karabat MU, Tuncer MC. Effects of hyaluronic acid on skin at the cellular level: a systematic review. Rev Assoc Med Bras. 2025;71(8):e20250208. — Systematic review of 45 studies found low-molecular-weight HA stimulates keratinocyte proliferation and migration while high-molecular-weight HA drives skin hydration, supporting topical HA as an effective skin-hydrating and barrier-supporting ingredient.
Bravo B et al., Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence, Dermatology and Therapy 2022;12(12):2657-2680 — HA-based cosmeceuticals reliably improve hydration and signs of skin aging
Lee SG et al., Hyaluronan Oligosaccharides Improve Rosacea-Like Phenotype through Anti-Inflammatory and Epidermal Barrier-Improving Effects, Annals of Dermatology 2020
Signals your skin to make more collagen. Quiet but real support for firmness and fine lines with consistent daily use.
Yang Y et al., Comprehensive evaluation of the efficacy and safety of a new multi-component anti-aging topical eye cream, Skin Research and Technology 2024;30(7):e13790 — 12-week study of active complex containing Matrixyl 3000 peptides showed significant improvement in hydration, elasticity, periorbital wrinkles
Aruan RR et al., Double-blind, Randomized Trial on the Effectiveness of Acetylhexapeptide-3 Cream and Palmitoyl Pentapeptide-4 Cream for Crow's Feet, Journal of Clinical and Aesthetic Dermatology 2023;16(2):37-43 — RCT of topical palmitoyl pentapeptide-4 (Matrixyl) for periorbital wrinkles
Imhof L, Leuthard D, Topical Over-the-Counter Antiaging Agents: An Update and Systematic Review, Dermatology 2021;237(2):217-229 — SR covering topical antiaging peptides
Pro-vitamin B5. Deeply hydrates and helps repair the skin barrier, calming dry or compromised skin.
Gao Y et al., Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment, Journal of Cosmetic Dermatology 2025;24(7):e70223 — double-blind RCT (n=60): panthenol mask decreased erythema, enhanced hydration, repaired barrier vs saline
Cho YS et al., Use of Dexpanthenol for Atopic Dermatitis-Benefits and Recommendations Based on Current Evidence, Journal of Clinical Medicine 2022;11(14):3943 — Korean-authored review; dexpanthenol improves barrier and reduces severity in mild-to-moderate AD
Heise R et al., Accelerated wound healing with a dexpanthenol-containing ointment after fractional ablative CO2 laser resurfacing of photo-damaged skin in a randomized prospective clinical trial, Cutaneous and Ocular Toxicology 2019;38(3):274-278 — RCT: dexpanthenol significantly faster wound closure vs petroleum jelly post-laser
A workhorse antioxidant that defends your skin from daily oxidative damage. Pairs especially well with vitamin C, and it's in nearly every good moisturizer for a reason.
Neves JR et al., Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs, Journal of Cosmetic Dermatology 2022;21(10):4462-4469 — tocopherol-containing antioxidant serum reduced pollution-induced damage and improved aging signs
Warshaw EM et al., Patch Testing With Tocopherol and Tocopherol Acetate: The North American Contact Dermatitis Group Experience, 2001 to 2016, Dermatitis 2021;32(5):308-318 — 15-year NACDG data: positive patch-test reactions to tocopherol rare given widespread cosmetic use
Lin FH et al., Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin, Journal of Investigative Dermatology 2005;125(4):826-832 — ferulic acid + vit C + vit E combo doubled photoprotection vs C+E alone (cross-listed; same paper cited for Ferulic Acid and Vit C)
Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.
Similar comparisons
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