Multi-vitamin + Antioxidants Ultra Riché Pm Treatment
What it's good for
Key actives from our research database. Click any to read the full evidence dossier.
Calms irritation and adds light hydration. The classic for sunburned or reactive skin.
Good for: Anti-inflammatory, Hydrating
A "universal antioxidant" that protects both the oily and watery parts of your skin. It's unique because it can recycle your Vitamin C and E, making them last longer. It also prevents "sugar-sag" (glycation) and reduces fine lines.
Good for: Antioxidant, Anti-aging
A botanical with real clinical wins for irritated, post-procedure, or recovering skin, with randomized-trial support behind its soothing reputation. Gentle enough for delicate, easily reactive skin and dry, sensitive patches.
Good for: Anti-inflammatory
Also called "cica," it calms redness, repairs the skin barrier, and speeds up recovery. The go-to for irritated or reactive skin.
Good for: Anti-inflammatory, Barrier repair
A fruit-derived AHA that exfoliates and antioxidizes. It shares the same basic mechanism as glycolic and lactic acid but is weaker gram-for-gram; in practice you'll see it doing dual duty (a little exfoliation plus pH stabilisation) in multi-acid toners and serums. When it appears low on an ingredient list, it's adjusting pH; higher up, it's contributing real exfoliation.
Good for: Exfoliating, Antioxidant
A naturally-occurring antioxidant your skin loses as you age. Topical CoQ10 restores some of what time depletes, supporting energy production in skin cells and softening wrinkle depth.
Good for: Antioxidant, Anti-aging
A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.
Good for: Hydrating
An ancient humectant and antimicrobial ingredient with a long research track record. Its sugar matrix and flavonoids help draw in moisture and support skin comfort; formulas pairing honey with beeswax and olive oil have shown improvement in dry, irritation-prone skin in controlled trials.
Good for: Anti-inflammatory, Anti-acne, Hydrating
A multitasker that calms redness, evens out skin tone, and helps oily skin balance out. One of the safest do-a-little-of-everything ingredients.
Good for: Brightening, Barrier repair, Anti-inflammatory
Pro-vitamin B5. Deeply hydrates and helps repair the skin barrier, calming dry or compromised skin.
Good for: Hydrating, Barrier repair
A plant-derived acid that blocks the enzyme your skin uses to make pigment, fading dark spots and post-acne marks. Clinical trials show it measurably reduces hyperpigmentation and improves skin luminosity, with significantly less irritation than stronger AHAs. A good option for sensitive skin that still wants a brightening acid.
Good for: Brightening, Antioxidant, Exfoliating
An "adaptogen" mushroom that helps skin cells handle stress at the gene level. Early-stage evidence but mechanistically interesting for anti-aging routines layered with vitamin C or peptides.
Good for: Antioxidant, Anti-aging
A grape-derived antioxidant that defends skin from daily oxidative damage and helps even out tone. Often paired with vitamins C and E in nighttime serums.
Good for: Antioxidant, Anti-aging, Brightening
Speeds up how fast your skin renews itself so old, dull cells shed faster and fresher skin shows through. Builds collagen over time, smoothing fine lines.
Good for: Anti-aging
A dry oil that absorbs quickly and brings a tiny trickle of vitamin-A-like activity. Good for scarring, post-acne marks, and barrier rebuild without feeling greasy.
Good for: Barrier repair, Antioxidant, Brightening
A rich, naturally occlusive plant butter from the African karite tree. Soothes dry, irritation-prone skin, refills the lipid barrier, and was well tolerated enough in randomized trials that most participants used it comfortably as a daily emollient.
Good for: Barrier repair, Hydrating, Anti-inflammatory
Brightens dull skin and helps fade dark spots. Also defends against everyday UV and pollution damage when worn under sunscreen.
Good for: Brightening, Antioxidant
A workhorse antioxidant that defends your skin from daily oxidative damage. Pairs especially well with vitamin C, and it's in nearly every good moisturizer for a reason.
Good for: Antioxidant
Evidence behind the ingredients
Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.
Calms irritation and adds light hydration. The classic for sunburned or reactive skin.
Huang YN et al., Effects of Aloe vera on Burn Injuries: A Systematic Review and Meta-Analysis of Randomized Controlled Trials, Journal of Burn Care & Research 2024;45(6):1536-1545 — topical aloe vera reduced burn wound-healing time
Tungkasamit T et al., Reduction in severity of radiation-induced dermatitis in head and neck cancer patients treated with topical aloe vera gel: A randomized multicenter double-blind placebo-controlled trial, European Journal of Oncology Nursing 2022;59:102164 — aloe vera reduced severity of moderate-to-severe radiation dermatitis
Sharma S et al., Second-Degree Burns and Aloe Vera: A Meta-analysis and Systematic Review, Advances in Skin & Wound Care 2022;35(11):1-9 — topical aloe vera shortened time to healing for second-degree burns
A "universal antioxidant" that protects both the oily and watery parts of your skin. It's unique because it can recycle your Vitamin C and E, making them last longer. It also prevents "sugar-sag" (glycation) and reduces fine lines.
Lee WJ et al., Anti-Inflammatory and Antioxidative Effects of Alpha Lipoic Acid on Cultured Human Sebocytes, Annals of Dermatology 2019
Beitner H, Randomized, placebo-controlled, double blind study on the clinical efficacy of a cream containing 5% alpha-lipoic acid related to photoageing of facial skin, British Journal of Dermatology 2003;149(4):841-9
A botanical with real clinical wins for irritated, post-procedure, or recovering skin, with randomized-trial support behind its soothing reputation. Gentle enough for delicate, easily reactive skin and dry, sensitive patches.
Deligiannidou GE et al. (Greece), An Update of Phytotherapeutic Advances of Marigold (Calendula officinalis L.) in Wound Healing, Plants (Basel) 2025 — peer-reviewed review of 2020-2025 experimental and clinical evidence on Calendula formulations for skin regeneration: healing rate, cell proliferation, inflammatory modulation
Effect of oral Calendula officinalis on second-degree burn wound healing (Iran), Scars Burns and Healing 2023
Siddiquee S et al., Efficacy of topical Calendula officinalis on prevalence of radiation-induced dermatitis: A randomised controlled trial, Australasian Journal of Dermatology 2021;62(1):e35-e40 — topical calendula reduced radiation-induced dermatitis
+−15 more ingredients
Also called "cica," it calms redness, repairs the skin barrier, and speeds up recovery. The go-to for irritated or reactive skin.
Hur N et al., A Randomized, Double-Blind, Placebo-Controlled Trial Assessing the Effects of Oral Centella asiatica Extract on Skin Aging-Related Parameters in Middle-Aged Korean Women, Nutrients 2026
Borowicz KK et al., Geroprotective Potential of Centella asiatica: Modulation of Cellular Aging, Nutrients 2026
Witkowska K et al., Topical Application of Centella asiatica in Wound Healing: Recent Insights into Mechanisms and Clinical Efficacy, Pharmaceutics 2024;16(10):1252 — modern hydrogel and nanostructured Centella delivery systems accelerate wound healing across wound types
A fruit-derived AHA that exfoliates and antioxidizes. It shares the same basic mechanism as glycolic and lactic acid but is weaker gram-for-gram; in practice you'll see it doing dual duty (a little exfoliation plus pH stabilisation) in multi-acid toners and serums. When it appears low on an ingredient list, it's adjusting pH; higher up, it's contributing real exfoliation.
Tang SC, Yang JH. Dual Effects of Alpha-Hydroxy Acids on the Skin. Molecules. 2018;23(4):863.
Yamamoto Y, Uede K, Yonei N, Kishioka A, Ohtani T, Furukawa F. Effects of alpha-hydroxy acids on the human skin of Japanese subjects: the rationale for chemical peeling. Journal of Dermatology. 2006 Jan;33(1):16-22. — Clinical-mechanistic study in Japanese subjects demonstrating AHA (including citric acid class) keratolytic and epidermal renewal effects as rationale for chemical peeling.
Bernstein EF, Underhill CB, Lakkakorpi J, et al. Citric acid increases viable epidermal thickness and glycosaminoglycan content of sun-damaged skin. Dermatologic Surgery. 1997 Aug;23(8):689-694. — Mechanistic study showing topical citric acid increased viable epidermal thickness and dermal glycosaminoglycans in sun-damaged skin, similar to glycolic acid and retinoic acid.
A naturally-occurring antioxidant your skin loses as you age. Topical CoQ10 restores some of what time depletes, supporting energy production in skin cells and softening wrinkle depth.
Li S et al., Ginsenoside Nanoliposomes Deliver Ergothioneine and Coenzyme Q10 to Address Skin Aging via Mitochondrial Mechanisms, Colloids and Surfaces B: Biointerfaces 2026
Lain ET, Agrawal N, Ruvolo E, Weise JM, Callender VD, The Role of Coenzyme Q10 in Skin Aging and Opportunities for Topical Intervention: A Review, Journal of Clinical and Aesthetic Dermatology 2024;17(8):42-47
Ayunin Q, Miatmoko A, Soeratri W, Erawati T, Susanto J, Legowo D, Improving the anti-ageing activity of coenzyme Q10 through protransfersome-loaded emulgel, Scientific Reports 2022;12(1):906 — topical CoQ10 protransfersomal emulgel increased collagen density and fibroblast count in UV-aged mouse skin
A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.
Danby SG et al., Different types of emollient cream exhibit diverse physiological effects on the skin barrier in adults with atopic dermatitis, Clinical and Experimental Dermatology 2022;47(6):1154-1164 — glycerol+urea emollient delivered superior barrier-strengthening and irritant protection
Youssef R et al., Glycerol 85% efficacy on atopic skin and its microbiome: a randomized controlled trial, Journal of Dermatological Treatment 2021;32(7):730-736 — topical glycerol 85% RCT on atopic skin
Evans NJ et al., Human axillary skin condition is improved following incorporation of glycerol into the stratum corneum from an antiperspirant formulation, Archives of Dermatological Research 2017;309(9):739-748 — 4% glycerol penetrated axillary SC, reduced irritation, improved hydration
An ancient humectant and antimicrobial ingredient with a long research track record. Its sugar matrix and flavonoids help draw in moisture and support skin comfort; formulas pairing honey with beeswax and olive oil have shown improvement in dry, irritation-prone skin in controlled trials.
Semprini A, Braithwaite I, Corin A, et al. Randomised controlled trial of topical kanuka honey for the treatment of acne. BMJ Open. 2016 Feb 1;6(2):e009448. — RCT: kanuka honey + antibacterial soap was NOT significantly more effective than antibacterial soap alone for acne; primary endpoint not met.
Jull AB, Cullum N, Dumville JC, Westby MJ, Deshpande S, Walker N. Honey as a topical treatment for wounds. Cochrane Database Syst Rev. 2015;(3):CD005083.
Mandal MD, Mandal S. Honey: its medicinal property and antibacterial activity. Asian Pac J Trop Biomed. 2011;1(2):154-160.
A multitasker that calms redness, evens out skin tone, and helps oily skin balance out. One of the safest do-a-little-of-everything ingredients.
Moro F et al., Skin Cancer Prevention and Antiaging: Role of Nicotinamide, International Journal of Molecular Sciences 2026
Passeron T et al., An Investigator-Blinded, Randomized Trial of a Broad-Spectrum Sunscreen Containing Sclareolide and Niacinamide, Dermatology and Therapy (Heidelberg) 2026
Vergilio MM et al., Topical Formulation with Niacinamide Combined with 5 MHz Ultrasound for Improving Skin Ageing, Current Medicinal Chemistry 2025
Pro-vitamin B5. Deeply hydrates and helps repair the skin barrier, calming dry or compromised skin.
Gao Y et al., Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment, Journal of Cosmetic Dermatology 2025;24(7):e70223 — double-blind RCT (n=60): panthenol mask decreased erythema, enhanced hydration, repaired barrier vs saline
Cho YS et al., Use of Dexpanthenol for Atopic Dermatitis-Benefits and Recommendations Based on Current Evidence, Journal of Clinical Medicine 2022;11(14):3943 — Korean-authored review; dexpanthenol improves barrier and reduces severity in mild-to-moderate AD
Heise R et al., Accelerated wound healing with a dexpanthenol-containing ointment after fractional ablative CO2 laser resurfacing of photo-damaged skin in a randomized prospective clinical trial, Cutaneous and Ocular Toxicology 2019;38(3):274-278 — RCT: dexpanthenol significantly faster wound closure vs petroleum jelly post-laser
A plant-derived acid that blocks the enzyme your skin uses to make pigment, fading dark spots and post-acne marks. Clinical trials show it measurably reduces hyperpigmentation and improves skin luminosity, with significantly less irritation than stronger AHAs. A good option for sensitive skin that still wants a brightening acid.
Markiewicz-Tomczyk A et al., Clinical Evaluation of Anti-Aging Effects of Combined Therapy - Azelaic Acid, Phytic Acid, and Vitamin C Applied Layer by Layer in Females, Journal of Cosmetic Dermatology 2022
Houshmand EB. Effect of glycolic acid, phytic acid, soothing complex containing emulsion on hyperpigmentation and skin luminosity: a clinical evaluation. J Cosmet Dermatol. 2021;20(3):776-780.
Sarkar R et al. Comparative Study of 35% Glycolic Acid, 20% Salicylic-10% Mandelic Acid, and Phytic Acid Combination Peels in the Treatment of Active Acne and Postacne Pigmentation. J Cutan Aesthet Surg. 2019;12(3):158-163.
An "adaptogen" mushroom that helps skin cells handle stress at the gene level. Early-stage evidence but mechanistically interesting for anti-aging routines layered with vitamin C or peptides.
Tao L, Tai M et al., A Ganoderma lucidum Extract Improves Mitochondrial Function in Aging Skin and Promotes Wound Healing, Clinical Cosmetic and Investigational Dermatology 2026 — Ganoderma lucidum extract reduced ROS, boosted mitochondrial energy production, and accelerated wound healing in aging skin (cell + animal models)
Dikmen Kucuk S et al., Cosmetic Potential of Ganoderma lucidum (Reishi) Extract in a Topical Cream Formulation, International Journal of Cosmetic Science 2026
Mohamed G et al., Unlocking the Therapeutic Potential of Ganoderma lucidum: From Bioactive Compounds to Clinical Translation, Phytotherapy Research 2026
A grape-derived antioxidant that defends skin from daily oxidative damage and helps even out tone. Often paired with vitamins C and E in nighttime serums.
Shi Y, Shen C, Zhang W, Efficacy and safety of a topical skincare regimen containing CE Ferulic serum and resveratrol BE serum following ablative fractional CO2 laser treatment, Journal of the European Academy of Dermatology and Venereology 2024;38 Suppl 6:18-25 — split-face RCT, resveratrol-containing serum reduced erythema and accelerated wound healing post-laser
Hecker A et al., The impact of resveratrol on skin wound healing, scarring, and aging, International Wound Journal 2022;19(1):9-28 — review of resveratrol's dermatological effects on wound healing, scarring, and photoaging
Lin MH et al., The bioactivities of resveratrol and its naturally occurring derivatives on skin, Journal of Food and Drug Analysis 2021;29(1):15-38 — review of cutaneous resveratrol activity in photoaging, melanogenesis, and dermatitis
Speeds up how fast your skin renews itself so old, dull cells shed faster and fresher skin shows through. Builds collagen over time, smoothing fine lines.
SCCS Revision of the Scientific Opinion on Vitamin A (Retinol, Retinyl Acetate, Retinyl Palmitate), SCCS/1639/21, final version adopted 24-25 October 2022
Chien AL et al. Biomarkers of Tretinoin Precursors and Tretinoin Efficacy in Patients With Moderate to Severe Facial Photodamage: A Randomized Clinical Trial. JAMA Dermatology. 2022;158(8):892-900. doi:10.1001/jamadermatol.2022.1891 — RCT comparing topical retinol precursors vs tretinoin for photoaging; both showed equivalent wrinkle reduction at week 24 with retinol formulation causing 6x less erythema than tretinoin.
MFDS Approved Functional Cosmetic Active — Retinol (anti-wrinkle). Korean Ministry of Food and Drug Safety, Cosmetic Functional Active Ingredient List — listed alongside Adenosine, Retinyl Palmitate, and Polyethoxylated Retinamide in the Korean Functional Cosmetics Codex anti-wrinkle category
A dry oil that absorbs quickly and brings a tiny trickle of vitamin-A-like activity. Good for scarring, post-acne marks, and barrier rebuild without feeling greasy.
Rossi M et al. (Italy), GinExtraMed: Focus on Rosa canina L. Extract Encapsulated into Glycethosomes and Allanthosomes for Accelerating Skin Wound Healing, Pharmaceutics 2025
Evaluation of a Retinol Nanoemulsion Gel Enriched with Black Seed and Rosehip Oils for Acne Management, Drug Research (Stuttgart) 2025 — topical retinol+rosehip+black seed gel evaluated for inflammatory acne management
Lin TK et al., Rosehip extract and wound healing: A review, Journal of Cosmetic Dermatology 2024
A rich, naturally occlusive plant butter from the African karite tree. Soothes dry, irritation-prone skin, refills the lipid barrier, and was well tolerated enough in randomized trials that most participants used it comfortably as a daily emollient.
O'Connor RJ et al., Clinical Evaluation of a Diaper Containing a Shea Butter-Based Emollient and Impact on Diapered Skin Erythema, Pediatr Dermatol 2025;42(3):532-538 — RCT n=271 infants, shea-butter diaper reduced dermatitis
Burnett CL, Bergfeld WF, Belsito DV, et al. Safety Assessment of Butyrospermum parkii (Shea)-Derived Ingredients as Used in Cosmetics. Cosmetic Ingredient Review Expert Panel Final Report.
Verallo-Rowell VM, Katalbas SS, Pangasinan JP. Natural (Mineral, Vegetable, Coconut, Essential) Oils and Contact Dermatitis. Curr Allergy Asthma Rep. 2016;16(7):51. — discussing shea butter unsaponifiable fraction NF-kB inhibition and dermatologic use.
Brightens dull skin and helps fade dark spots. Also defends against everyday UV and pollution damage when worn under sunscreen.
Krutmann J et al. PINGing Sunshine: A Review of the Evidence for Adding Non-Filtering Photoprotective Ingredients to Sunscreens. Photodermatol Photoimmunol Photomed. 2025;41(6). — Review of Photoprotective INGredients (PINGs); L-ascorbic acid (vitamin C) identified as a top-ranked PING demonstrating efficacy across multiple photodamage endpoints.
Pullar JM et al., The roles of vitamin C in skin health, Nutrients 2017;9(8):866 — concluded topical efficacy "poorly understood"; supports dietary vitamin C
Lee JH et al., Effects of VitabridC12 on Skin Inflammation, Annals of Dermatology 2017
A workhorse antioxidant that defends your skin from daily oxidative damage. Pairs especially well with vitamin C, and it's in nearly every good moisturizer for a reason.
Neves JR et al., Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs, Journal of Cosmetic Dermatology 2022;21(10):4462-4469 — tocopherol-containing antioxidant serum reduced pollution-induced damage and improved aging signs
Warshaw EM et al., Patch Testing With Tocopherol and Tocopherol Acetate: The North American Contact Dermatitis Group Experience, 2001 to 2016, Dermatitis 2021;32(5):308-318 — 15-year NACDG data: positive patch-test reactions to tocopherol rare given widespread cosmetic use
Lin FH et al., Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin, Journal of Investigative Dermatology 2005;125(4):826-832 — ferulic acid + vit C + vit E combo doubled photoprotection vs C+E alone (cross-listed; same paper cited for Ferulic Acid and Vit C)
Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.
Layering conflicts
Ingredients in this product that can react with common actives. Avoid stacking unless noted.
- Salicylic Acidhigh
Retinol + salicylic acid can over-exfoliate and damage the barrier. Alternate nights.
- Glycolic Acidhigh
Retinol + glycolic acid is a classic barrier-buster. Use on different nights.
- Lactic Acidmedium
Retinol + lactic acid is gentler than glycolic but still alternate nights to be safe.
- Mandelic Acidmedium
Retinol + mandelic acid — alternate nights to preserve barrier integrity.
- Benzoyl Peroxidemedium
Benzoyl peroxide can break down retinol. Use one in the morning and the other at night, or pick a stabilized formula made to combine them.
Similar comparisons
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